Protein Alignment Sytbeta and syt6a

DIOPT Version :10

• Sequence 1: NP_648734.1
• Gene: Sytbeta / 39630
• FlyBaseID: FBgn0261090
• Length: 602
• Species: Drosophila melanogaster
• Sequence 2: XP_017209198.1
• Gene: syt6a / 100149310
• ZFINID: ZDB-GENE-090601-2
• Length: 537
• Species: Danio rerio
• Alignment Length: 535
• Identity: 152/535 - (28%)
• Similarity: 228/535 - (42%)
• Gaps: 152/535 - (28%)

  Fly    95 IGSVSAGSVSDSC---------DLPTDSEEVAIAKECQPIQPASQLHGMHGGMGLNHHHMGTVSA 150
            :.|.||....|.|         ..|..||.:|..||..|:   :.:..:...:.::|
Zfish    91 LSSSSAALAPDDCPSPHIPSVLPSPQPSEAMATEKEKYPM---ASMGFLEAAVKISH-------- 144

  Fly   151 TGTDILRGPAEVFHSPLHLHHQSRSFPPRLQRTPSISSQSSVDSAPSRHSGHRGSSPQIRTFGPD 215
            |..||   ||||..| :..|.        |:||..:..|::..::.:|||
Zfish   145 TSPDI---PAEVQLS-MREHF--------LRRTQRMQRQTTEPASSTRHS--------------- 182

  Fly   216 GRSSLPSEPGFPHHLARSPSPMRTISLDARCGSPAHSADPGDLRTPSPSQSSLASLAGGSGMGGS 280
                     .|..||   |..|:..|||.        .|..|:
Zfish   183 ---------SFKRHL---PRQMQVSSLDL--------GDDYDV---------------------- 205

  Fly   281 SAGKGVAGGRCLSPLLIPPRSQPGVDPAMGPASPLGALQPDLYRMPDGPVYLTAPESSHA----- 340
                               ..||         :.:|.::|:||:.      :|......|
Zfish   206 -------------------DEQP---------TSIGRIKPELYKQ------MTTENDESANSKGG 236

  Fly   341 --VGRLHLRVKYDYHLFDLTVHLIEAHNLSPIEEGGFRDPYVRLMLQPEVDSRKRQTHIHRGESN 403
              .|:::..::|||....|.|.:::|.:|...:..|..||||::.|.|: ..:|.||.:||...|
Zfish   237 KNCGKINFSLRYDYENEMLLVKILKAFDLPAKDLCGSSDPYVKIYLLPD-RKQKFQTRVHRKTLN 300

  Fly   404 PYFDQHFKFPVSRDQLQGKELILQVLDYDRYSHNDIIGEVRISVDGL----DLSKSVEIWGDLLR 464
            |.||:.|:|||..|:|..::|.|.|.|:||:|.:|:||||  .:|.|    |||:...||.|:..
Zfish   301 PTFDESFQFPVPYDELAVRKLHLSVFDFDRFSRHDMIGEV--ILDNLFEVSDLSRETSIWRDIQY 363

  Fly   465 TKKPKEDRPELLCSLNYLPQAERLTVVIMKARNLDTL-----QEPYVKIYLIQNGKRIKKKKTSI 524
            ......|..|::.||.|||.|.|||:.::|.|||..:     .:||||:.||.:|:|:|||||:.
Zfish   364 ATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLICDGRRLKKKKTTT 428

  Fly   525 TKSDDPTNPIWNEAFTFNLQSN-----YLHNAAIEIYVVGAGSEATEIGCCGLGPQESGTGCQHW 584
            .|  :..||.:|||..|::...     .||.:.::..:||...   .||.|.||....|.|..||
Zfish   429 KK--NTLNPTYNEAIIFDIPPESMDQVSLHISVMDYDLVGHNE---IIGVCRLGCGAEGLGRDHW 488

  Fly   585 HDMINNARKPTAMWH 599
            ::|:...|||.|.||
Zfish   489 NEMLAYPRKPIAHWH 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sytbeta	NP_648734.1	PHA03307	39..>267	CDD:223039	39/180 (22%)
		C2	341..463	CDD:472691	50/125 (40%)
		C2B_Synaptotagmin	473..601	CDD:175975	54/137 (39%)
syt6a	XP_017209198.1	C2A_Synaptotagmin-1-5-6-9-10	238..363	CDD:176031	50/127 (39%)
		C2B_Synaptotagmin-3-5-6-9-10	372..505	CDD:176048	54/137 (39%)