DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Reck and tmeff1b

DIOPT Version :9

Sequence 1:	NP_001261853.1	Gene:	Reck / 39629	FlyBaseID:	FBgn0036463	Length:	1071	Species:	Drosophila melanogaster
Sequence 2:	NP_001020472.1	Gene:	tmeff1b / 553511	ZFINID:	ZDB-GENE-050706-143	Length:	364	Species:	Danio rerio

Alignment Length:	217	Identity:	49/217 - (22%)
Similarity:	75/217 - (34%)	Gaps:	74/217 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   707 CTKQQCRLPGFVDSGYTSLPC----NCPAHYVPVCGSNGNTYPSACVAKCHLPEGDYVYGACNAR 767
            |....||..|...:....:.|    .|..:|:||||:||:||.:.|..|         ..|||.:
Zfish    68 CDATTCRFNGICQNNGGDIKCVCQFQCSKNYIPVCGTNGDTYQNECYLK---------QAACNQQ 123

  Fly   768 NACQAA------PPNSCPSGTQCLD------SRKVCLASMQRPCLQYVCVNATASNCSTFHQGEV 820
            .:...|      |.:|..||....|      .:||                   :.||....|..
Zfish   124 KSIVLANEGPCDPDSSSGSGNGEFDGSGLESGKKV-------------------TKCSNCKYGAE 169

  Fly   821 CDSQGRTYPNACALLKANPQGQVAYWSACQSSRFNTSPSPVCGINGVTY------KSSYAARAEY 879
            ||..... .::|               :|:......:.:||||.:|.:|      :.:...:.|.
Zfish   170 CDEDAED-EDSC---------------SCKIDCSGHNENPVCGTDGNSYHNPCLVREASCMKQEQ 218

  Fly   880 VLVDYVGRC--------REVGL 893
            :.|.::|||        .|.||
Zfish   219 IDVKHLGRCPDKDKSKKTEAGL 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Reck	NP_001261853.1	KAZAL_FS	729..>753	CDD:238052	12/23 (52%)
tmeff1b	NP_001020472.1	KAZAL	89..134	CDD:197624	16/53 (30%)
		KAZAL	182..227	CDD:197624	10/44 (23%)
		PHA02887	<263..300	CDD:165214
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900