Protein Alignment Reck and F29G6.1

DIOPT Version :9

• Sequence 1: NP_001261853.1
• Gene: Reck / 39629
• FlyBaseID: FBgn0036463
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_509920.3
• Gene: F29G6.1 / 181339
• WormBaseID: WBGene00009257
• Length: 1189
• Species: Caenorhabditis elegans
• Alignment Length: 1117
• Identity: 211/1117 - (18%)
• Similarity: 342/1117 - (30%)
• Gaps: 432/1117 - (38%)

  Fly    48 KSNASVDHHRHAPSSGSKKNSRSHSVSLDSDDYDWLDADTSEAIDSSEVTAVESIRSPGESYDIF 112
            |::||.....|:|.:   :|..:.:.|:...|..|                     .|
 Worm   249 KTSASKHRENHSPLT---RNDLNRACSIKECDKSW---------------------DP------- 282

  Fly   113 TCCNQVFGSCRTACENLSLVEFATGTGGDNRDELHR-YCQLHQVEFWTC-VNQ----TFDAITRG 171
                        .|              |.|:..|: .||.   :|:.| :|:    ..|....|
 Worm   283 ------------VC--------------DTRNRTHKNVCQF---KFFACKINKIDGSVIDIAHSG 318

  Fly   172 ADWSGRRCC-----QFGVLPHC--RNVCATSTRSPVQ-NC---RRSDEQT----LYDCLERQ--- 218
            |..:.:..|     ....:|.|  ||:...:..|.:| ||   ...||:.    :..|.||.
 Worm   319 ACRARKSTCITCPKDEKKIPICDNRNMTHPTLCSFIQYNCEARNNEDEERVLVHIKSCHERSPQF 383

  Fly   219 EAADQCCGQARTSECLEACRAVFEPANDNHDHV----DINGACGDRNADVIQ--------CVNNH 271
            ...|:.|  .||  |....:.|.:.||:.|.::    ..|  |..|...:..        ||.|.
 Worm   384 TLKDEIC--PRT--CSRDVKPVCDEANNTHQNLCHFQQYN--CNMRKLGIRSPYLRYLRPCVKNR 442

  Fly   272 TDMTPLANAEQYIPCCEY---SSKEHCRHTCRNLLHQNATLMERSEVI--FGRLEAAGCGSPLPQ 331
            .....:.|.|........   :||.....|..:.|.|.....:.:.::  |.::..:...:|.|.
 Worm   443 KIDNAVENVEMRATVSNVVIKTSKSVAESTTTSQLKQTVASEKTTFIVSAFEKVLKSTTSTPSPS 507

  Fly   332 LPFWQCFLTVTGKLYVP----------------------------------------------GG 350
            ...      ||..:.||                                              ..
 Worm   508 STI------VTTTIKVPTVTFSTLPDPTTKSILEIEIETTTPLDVAFFDCPKPNCPTDGQPVCDS 566

  Fly   351 SGRAGGSLAQGRIS-----GQGGSL---AEPNHLGMDAAKRQCCEQASSHKCRRLCNQIFTSNWW 407
            :|...|:|.:...|     .:|..:   .|.|.:..:|.:..|.:  ..|.   :|...|
 Worm   567 AGNLHGNLCEFTYSRCIAASKGHQIHIATEENCISKEACQMPCTD--DKHP---ICASDF----- 621

  Fly   408 DARSSFEN-------ECMDQPGERELR-RCIESVDAPCELGCQGLSFCSNFNNRPTELFRSCTPE 464
               |::||       :|:|...|...: :|.|.:|:||.|..:         |.|.|.| .|..:
 Worm   622 ---STYENLCQFRKQKCLDSELEVLFKGKCSECLDSPCALPAE---------NSPDESF-VCLED 673

  Fly   465 HDAAAREDWQLLQ---QRGTVRVLGQELFIKNTSRCAPDKWRALVCALQLKPCTRVGLFNGICSE 526
            ....:..::|:|.   :||    .|..|.::....|.|.   ...|..: ||       :.:|::
 Worm   674 QSTKSLCEYQMLSCIFERG----YGVNLTVQYIGVCCPP---VESCDTE-KP-------DPVCTD 723

  Fly   527 DCHELLDECLDWTLQHQRPKDICSRLKEKDDDDSPLPCISLESYLKPGDASPEEFQGITSPCAQK 591
            .....|.||.                            :::|:                  |..|
 Worm   724 SGATFLTECE----------------------------LNIEN------------------CKLK 742

  Fly   592 PCNGSEVCILQRGGNQGYSCIPGCNLGQDSKLFVPFGSYVRLGKSNLHKKLEVGQFPLAEHIVCS 656
            ..:..::.::.:|            :.:...|...|.|.....|.|:..|.| ..|
 Worm   743 KLDQPKLVVVSQG------------ICEKDMLTDDFSSNRNFQKPNIEFKRE-NTF--------- 785

  Fly   657 CGLQGRLEQCQPLPSYMHAHCTLPGARSY-----RHGSSFYLECNLCSCFAGEITCTKQQCR-LP 715
                               :|::....||     .:|.:|...|:|          .|:.|. ..
 Worm   786 -------------------NCSMECDNSYDPLCGTNGVTFTNACSL----------QKEICESAN 821

  Fly   716 GFVDSGYTSLPC--NCPAHYVPVCGSNGNTYPSAC---VAKCHLPE---GDYV----YGACNARN 768
            ..::..||.:.|  |||:.:.|||.|.|:|:.:.|   |.:| :.|   ||.:    :..||...
 Worm   822 STIEVAYTGMCCDTNCPSDFSPVCDSKGSTHQNICHFGVKRC-IAERTFGDVLTIDKFEVCNEVK 885

  Fly   769 ACQAAPPNSCPSGTQCLDSRKVCLASMQR----------PCLQYVCVNATA-------------- 809
            .|.    |:||.     :...||.::.|.          .||  |..|.|.
 Worm   886 ECN----NACPK-----EYSPVCASNGQNIVNECELDKIRCL--VENNVTTGDKLVKDYDGECCR 939

  Fly   810 -SNCSTFHQGEVCDSQGRTY-------PNACALLKANPQG-QVAYWSACQSSRFNTSPSPVCGIN 865
             .||.......|||::|.|:       .|||..:|.|.:. ||:|...|.:...:...:|||. .
 Worm   940 IENCDISVFSPVCDTEGVTHANMCLMDQNACIQMKKNKKTIQVSYQGQCCNQPCDEDKTPVCD-G 1003

  Fly   866 GVTYKS------------------SYAARAEYVLVDYVGRCREVGLLVSDMG-----------RR 901
            .:|:.:                  |.|...|..|:. .|.|...|.:....|           ||
 Worm  1004 TITHPNICRFRIAQCEAERVNKTLSIAYSGECCLLP-KGECESSGAVCDSEGQTHMNHCVYQQRR 1067

  Fly   902 CRTVKCPAPVSKHCRLIVPPGACCPL--CAGGAFRIIYSRKQ--------------FDRAMYGLR 950
            |..    ..:|:....||..|.||.|  |......:..||.:              ||:    :.
 Worm  1068 CMA----QTISQKTLNIVHTGECCALASCPKTGQPVCDSRGRTHDSLCHFHNSKCIFDK----IH 1124

  Fly   951 AQSSTL-LTLQG 961
            .|::|| |..||
 Worm  1125 TQNTTLTLDYQG 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reck	NP_001261853.1	KAZAL_FS	729..>753	CDD:238052	10/26 (38%)
F29G6.1	NP_509920.3	KAZAL_FS	40..79	CDD:238052
		KAZAL_FS	133..>168	CDD:294071
		KAZAL	274..320	CDD:197624	14/102 (14%)
		KAZAL	389..>424	CDD:197624	10/40 (25%)
		KAZAL	550..599	CDD:197624	6/48 (13%)
		KAZAL	605..648	CDD:197624	10/55 (18%)
		KAZAL	786..832	CDD:197624	11/55 (20%)
		KAZAL	833..881	CDD:197624	16/48 (33%)
		KAZAL	886..937	CDD:197624	12/61 (20%)
		KAZAL	941..988	CDD:197624	15/46 (33%)
		KAZAL	1092..1138	CDD:197624	11/49 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5473
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810