Protein Alignment Reck and SPINK5

DIOPT Version :9

• Sequence 1: NP_001261853.1
• Gene: Reck / 39629
• FlyBaseID: FBgn0036463
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001121170.1
• Gene: SPINK5 / 11005
• HGNCID: 15464
• Length: 1094
• Species: Homo sapiens
• Alignment Length: 615
• Identity: 119/615 - (19%)
• Similarity: 189/615 - (30%)
• Gaps: 204/615 - (33%)

  Fly   392 HKCRRLCNQIFTSNWWDARSSFENECMDQPGERELRRCIESVDAPCELGCQGLSFCSNFNNRPTE 456
            :|| .||.:||..     |.|.||...||    .|.:..|......|:    :..||.:.|:...
Human   256 NKC-ALCAEIFKQ-----RFSEENSKTDQ----NLGKAEEKTKVKREI----VKLCSQYQNQAKN 306

  Fly   457 LFRSCTPEHDAAAREDWQL-----------------LQQRGTVRVLGQELFIKNTS---RCAPDK 501
            ....||.|:|.....|.::                 .:::...|...:....|.||   .|:  :
Human   307 GILFCTRENDPIRGPDGKMHGNLCSMCQAYFQAENEEKKKAEARARNKRESGKATSYAELCS--E 369

  Fly   502 WRALV------CALQLKP------------CTRVGLF----------------NGICSEDCHELL 532
            :|.||      |..:..|            |:...:|                |...|:......
Human   370 YRKLVRNGKLACTRENDPIQGPDGKVHGNTCSMCEVFFQAEEEEKKKKEGKSRNKRQSKSTASFE 434

  Fly   533 DECLDWTLQHQRPKDICSRLKEKDDDDSP------LPCISLESYLKPGD-----ASPEEFQGITS 586
            :.|.::....:..:..|:|  |.|....|      ..|...|::.:..:     |..|..:.|.|
Human   435 ELCSEYRKSRKNGRLFCTR--ENDPIQGPDGKMHGNTCSMCEAFFQQEERARAKAKREAAKEICS 497

  Fly   587 PCAQKPCNGSEVCILQ----RG------GNQGYSCIPGCNLGQDSKLFVPFGSYVRLGKSNLHKK 641
            ....:..||:.:|..:    ||      ||:...|.....|.::.|            |::..:|
Human   498 EFRDQVRNGTLICTREHNPVRGPDGKMHGNKCAMCASVFKLEEEEK------------KNDKEEK 550

  Fly   642 LEVGQFPLAEHIVCSCGLQGRLEQCQPLPS-YMH------AHCT-----LPGARSYRHGSSFYLE 694
            .:|.    ||.:        :.|..|.|.| |.|      ..||     :.|.....||::
Human   551 GKVE----AEKV--------KREAVQELCSEYRHYVRNGRLPCTRENDPIEGLDGKIHGNT---- 599

  Fly   695 CNLCSCFAGEITCTKQQCRLPGFVDSGYTSLPCN------------CPAHYVPVCGSNGNTYPSA 747
            |::|..|..:....|::......|........|:            |.....||.|.:|.|:.:.
Human   600 CSMCEAFFQQEAKEKERAEPRAKVKREAEKETCDEFRRLLQNGKLFCTRENDPVRGPDGKTHGNK 664

  Fly   748 CVAKC------------HLPEGDYVYGACNARNACQAAPPNSCPSGTQCLDSRKVCLASMQRPCL 800
            | |.|            ...|.|       .|||  |...:|...|           .:.|..|.
Human   665 C-AMCKAVFQKENEERKRKEEED-------QRNA--AGHGSSGGGG-----------GNTQDECA 708

  Fly   801 QYVCVNATASNCSTFHQGEVCDSQGRTYPNACALLKANPQGQVAYWSACQSSRFNTSPS------ 859
            :|...........|.....|.|:.|::|.|.|.:.||..:.:....:....||.|.:.|
Human   709 EYREQMKNGRLSCTRESDPVRDADGKSYNNQCTMCKAKLEREAERKNEYSRSRSNGTGSESGKDT 773

  Fly   860 --------------------PVCGINGVTY 869
                                ||.|.:|.|:
Human   774 CDEFRSQMKNGKLICTRESDPVRGPDGKTH 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reck	NP_001261853.1	KAZAL_FS	729..>753	CDD:238052	9/35 (26%)
SPINK5	NP_001121170.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810