Protein Alignment Reck and reck

DIOPT Version :10

• Sequence 1: NP_648733.2
• Gene: Reck / 39629
• FlyBaseID: FBgn0036463
• Length: 1071
• Species: Drosophila melanogaster
• Sequence 2: NP_001410782.1
• Gene: reck / 100334698
• ZFINID: ZDB-GENE-070117-37
• Length: 955
• Species: Danio rerio
• Alignment Length: 1022
• Identity: 353/1022 - (34%)
• Similarity: 504/1022 - (49%)
• Gaps: 145/1022 - (14%)

  Fly   111 IFTCCN---QVFGS--------------CRTACENLSLVEFATGTGGDNRDELHR---YCQLHQV 155
            :..||.   .||..              ||.|||.|:.:...:..    |..|||   ||.....
Zfish    10 VLLCCRFWALVFSQDQSCCVHHAADIPRCRDACEQLASIRSESRL----RHLLHRLPSYCPETLS 70

  Fly   156 EFWTCVNQTFDAITRGAD-WSGRRCCQFGVLPHCRNVC--ATSTRSPVQNCRRSDEQTLYDCLER 217
            |.|.|:|.:....:|.:| |.|..||:..:...||..|  |:|.....:.|::..|..||.|:.:
Zfish    71 ELWICINNSLPGASRKSDGWVGLGCCELAISAECRRDCKQASSKNDISKVCKKDTENPLYSCITK 135

  Fly   218 QEAADQCCGQA-RTSECLEACRAVFEPANDNHDHVD----INGACGDRNADVIQCVNNHTDMTPL 277
            .|....||..| |.:.|.|.|:|:|.  .|:...|.    :...|...:..:|.||.|:|.:.|.
Zfish   136 NEMGSVCCSYAGRHTTCREYCQAIFR--TDSSPTVSQISAVKEYCQSVSPPLILCVENYTRLHPT 198

  Fly   278 ANAEQYIPCCEYSSKEHCRHTCRNLLHQNATLMERSEVIFGRLEAAGCGS-PLPQLPFWQCFLTV 341
            ......:.||:.:.:.||:..|:.:|.   ||....|::.|.:  :.||| ||||.|.|||||
Zfish   199 HRPIDSLHCCDRAEEAHCQLACKRILR---TLSTEQEIMDGLI--SECGSQPLPQDPLWQCFL-- 256

  Fly   342 TGKLYVPGGSGRAGGSLAQGRISGQGGSLAEPNHLGMDAAKRQCCEQASSHKCRRLCNQIFTSNW 406
             |..:.|..:......:|:                 ||:||..||.:|::..||.:|.:|.||
Zfish   257 -GSAHPPANTDPESPPIAK-----------------MDSAKLHCCFKANTSICRNMCVEISTS-- 301

  Fly   407 WDARS--SFENECMDQPGERELRRCIESVDAPCELGCQGLSFCSNFNNRPTELFRSCTPEHDAAA 469
            |..:|  .|:..|...|.|.:|..|:..|..||:|||:.||:|:|||||||||||||..:.|..|
Zfish   302 WGTQSWQEFDQHCEYNPVEMDLITCLADVREPCQLGCKELSYCTNFNNRPTELFRSCNVQSDQGA 366

  Fly   470 REDWQLLQQRGTVRVLGQELFIKNTSRCAPDKWRALVCALQLKPCTRVGLFNGICSEDCHELLDE 534
            ..|:: |...|::|:....:.:.:..||.|:.|:.:.||||:|||......:.||..||.|:|.:
Zfish   367 LNDFK-LWSNGSIRMPLMNIPVLDIRRCRPEMWKTVACALQIKPCYSRSRGSVICRSDCVEILRQ 430

  Fly   535 CLDWT--LQHQRPKDICSRLKEKDDDDSPLPCISLESYLKPG--DASPEEFQGITSPCAQKPCNG 595
            |.|..  .:.|.|:.||..|...||   |..||.|..||...  ::|.||   :..||...||..
Zfish   431 CGDRRRFAEAQTPERICDLLSPTDD---PERCIPLNRYLTASELESSVEE---VIHPCNPNPCPS 489

  Fly   596 SEVCILQRGG-NQG-----YSCIPGCNLGQDSKLFVPFGSYVRLGKSNLHKKLEVGQFPLAE--- 651
            |.:|.:.|.| :.|     |.|:|||.||:.|:..||  :..||            |.|:..
Zfish   490 SHLCHVNRKGCHVGHDCLPYYCVPGCKLGEASEFLVP--ADARL------------QVPVHSAQP 540

  Fly   652 --HIVCSCGLQGRLEQCQPLPSY-MHAHCTLPGARSYRHGSSFYLECNLCSCFAGEITCTKQQC- 712
              :.||.||..||||.|..:|.: ....|.:.|.|. .|||||.::||.||||||:..|:.:||
Zfish   541 GCYEVCVCGQSGRLENCAEMPCFDTSKSCQIAGQRR-SHGSSFRVDCNPCSCFAGDAVCSSRQCV 604

  Fly   713 ---------RLPGFVDSGYTSLPCNCPAHYVPVCGSNGNTYPSACVAKC-HLPEGDYVYGACNAR 767
                     ||       :|.|||.|..|:||||..||.||||||||:| ...:..:|:|:|.:.
Zfish   605 RSDSSEEDRRL-------FTGLPCGCADHFVPVCAGNGRTYPSACVARCVGFTDSQFVFGSCRSF 662

  Fly   768 NACQAAPPNSCPSGTQCLDSRKVCLASMQR-PCLQYVCVNATASNCSTFHQGEVCDSQGRTYPNA 831
            :.|.   ||.|....:|:..|:|||..:.. ||.||.|| :..|:|.......|||:....:.|.
Zfish   663 DPCS---PNPCQRNQRCVPRRQVCLTDLSEFPCPQYECV-SRPSSCDQKLLDPVCDTDNMEHANL 723

  Fly   832 CALLKANPQGQ-VAYWSACQSSRFNTSPSPVCGINGVTYKSSYAARAEYVLVDYVGRCREVGL-- 893
            |.|   |.:|: :||...||.:  ...|..||..||.:|.:...|.:|.|.|||.|||..|||
Zfish   724 CVL---NLRGKTLAYSGHCQDA--CRRPREVCAHNGESYSTVCEAFSERVAVDYQGRCHAVGLES 783

  Fly   894 -LVSDMGRRCRTVKCPAPVSKHCRLIVPPGACCPLCAGGAFRIIYSRKQFDRAMYGLRAQSSTLL 957
             ..||.|  |..|.||...|..|:.:.|||||||:|| |..||::::.|.:......|.|.   :
Zfish   784 EFGSDSG--CNAVPCPPLASDACQPVTPPGACCPVCA-GMLRILWNKAQMNIFAKLNRDQP---V 842

  Fly   958 TLQGVLQQLDGLVQVSECQLTGFLTMEVGIFVAIVPSSSIKRPTHLQLEACAREAEKISSLINAQ 1022
            :|..:|:.|...|.|.:|.:.|:|::...|.:.|.|..  ::||.||:|||::|||||.||||:.
Zfish   843 SLHDILKILRLHVSVPQCDIFGYLSINSEIIILIAPVD--QQPTPLQIEACSKEAEKIDSLINSG 905

  Fly  1023 SPRITTNLALSCLTVSHLLEPTPNGATSYGPHAIWILPLLLLVSRVI 1069
            ||.:.:::.||....|.|...:...::..   :|.:..||||.|.::
Zfish   906 SPTLVSHVPLSAFLSSELQLSSVRSSSCV---SISVCVLLLLCSLIL 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Reck	NP_648733.2	MFS	<727..791	CDD:475125	27/64 (42%)
		KAZAL_FS	729..>753	CDD:238052	17/24 (71%)
reck	NP_001410782.1	5 X Knot repeats. /evidence=ECO:0000250|UniProtKB:O95980	28..326		97/330 (29%)
		MFS	<621..659	CDD:475125	20/37 (54%)