DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and PRE5

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_014045.1	Gene:	PRE5 / 855362	SGDID:	S000004931	Length:	234	Species:	Saccharomyces cerevisiae

Alignment Length:	199	Identity:	43/199 - (21%)
Similarity:	80/199 - (40%)	Gaps:	26/199 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCG-------AGTAADTEMT 94
            |.|:..||:......:|          :...:|..::....|.|..|.       ||.|.|..:.
Yeast    30 KQGSVTVGLRSNTHAVL----------VALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARVL 84

  Fly    95 TDLISSQLELHRLQTDREVRVVAANTML----KQMLFRYQGH-ISAALVLGGVDKTGPHIYSIHP 154
            ::.:..|.....|..:|::.|..|..:|    ::....|.|. ....|::.|.||:|.|:....|
Yeast    85 SNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDKSGAHLLEFQP 149

  Fly   155 HGSSDKLPYATMGSGSLAAMTVFESRW----KPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLC 215
            .|:..:|....:|:.|..|.|..|...    |.|.:.:|..|...:||:..:.::..:..|:.:.
Yeast   150 SGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRDESLTVDNLSIA 214

  Fly   216 VIRK 219
            ::.|
Yeast   215 IVGK 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	41/194 (21%)
		proteasome_beta_type_7	42..228	CDD:239732	41/194 (21%)
		Pr_beta_C	232..264	CDD:289249
PRE5	NP_014045.1	Ntn_hydrolase	6..217	CDD:412394	42/196 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900