DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosbeta2 and PRE7

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_009512.1	Gene:	PRE7 / 852239	SGDID:	S000000137	Length:	241	Species:	Saccharomyces cerevisiae

Alignment Length:	221	Identity:	54/221 - (24%)
Similarity:	95/221 - (42%)	Gaps:	39/221 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 GTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQLE 103
            |.||:||..:|..:|..|||......::.:...|:.....||.....|.|||.:.......:.::
Yeast    28 GGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKRFKNSVK 92

  Fly   104 -LHRLQTDREVRVVAANTMLKQML-----FRYQGHISAALVLGGVDKTGP-HIYSIHPHGSSDKL 161
             .|....|:::.:.:|...::.:|     |.|..|    .::.|:|:.|. .:||..|.||.::
Yeast    93 WYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVH----TIIAGLDEDGKGAVYSFDPVGSYER- 152

  Fly   162 PYATMGSGSLAAMTV---------FESRWKPD-----------LSEEEGKKLVRDAIASGVFNDL 206
              ....:|..||..:         |:::::|.           ||.||..|||||:..|.....:
Yeast   153 --EQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHI 215

  Fly   207 GSGSNIDLCVIRKGSV--EYLRNYEL 230
            ..|..:::.::.|..|  |:   |||
Yeast   216 QVGDGLEILIVTKDGVRKEF---YEL 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	52/218 (24%)
		proteasome_beta_type_7	42..228	CDD:239732	49/214 (23%)
		Pr_beta_C	232..264	CDD:289249
PRE7	NP_009512.1	proteasome_beta_type_1	21..241	CDD:239726	54/221 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810