DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and psmb7

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	XP_021324576.1	Gene:	psmb7 / 64278	ZFINID:	ZDB-GENE-001208-4	Length:	286	Species:	Danio rerio

Alignment Length:	271	Identity:	180/271 - (66%)
Similarity:	211/271 - (77%)	Gaps:	16/271 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GFNFDNCKRNATL----LNRGFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKI 73
            ||:|:||:|||.|    ...||..|...||||||.||:|||||:||||||||||.||:||||:||
Zfish    13 GFSFENCRRNALLEADITKLGFSSPAARKTGTTICGIVYKDGVVLGADTRATEGMIVADKNCSKI 77

  Fly    74 HYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISAALV 138
            ||::.|||||||||||||||||.:|||.||||.|.|.|..||..||.|||||||||||:|.||||
Zfish    78 HYISPNIYCCGAGTAADTEMTTQIISSNLELHSLSTGRLPRVATANRMLKQMLFRYQGYIGAALV 142

  Fly   139 LGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVF 203
            |||||.||||:|||:||||:|||||.||||||||||.|||.|::||:.||:.|.|||||||:|:|
Zfish   143 LGGVDCTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDRYRPDMEEEDAKSLVRDAIAAGIF 207

  Fly   204 NDLGSGSNIDLCVIRKGSVEYLRNYELANKKGKRQ--LD-------YRFKTGTSTVLHTNIKDL- 258
            ||||||||||:|||.||.|:|||.:::|||||.|:  ||       ||:|.||:.||...:..|
Zfish   208 NDLGSGSNIDVCVITKGKVDYLRPHDIANKKGVREDKLDGRPVTGSYRYKHGTTGVLSKAVTPLN 272

  Fly   259 --LVTERVQAV 267
              :|.|.||.:
Zfish   273 LDMVEESVQTM 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	143/189 (76%)
		proteasome_beta_type_7	42..228	CDD:239732	143/185 (77%)
		Pr_beta_C	232..264	CDD:289249	17/43 (40%)
psmb7	XP_021324576.1	proteasome_beta_type_7	44..232	CDD:239732	145/187 (78%)
psmb7	XP_021324576.1	Pr_beta_C	237..280	CDD:315191	16/42 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	296	1.000	Domainoid score	I1443
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2093
Inparanoid	1	1.050	352	1.000	Inparanoid score	I2227
OMA	1	1.010	-	-		QHG53608
OrthoDB	1	1.010	-	-		D415498at33208
OrthoFinder	1	1.000	-	-		FOG0001188
OrthoInspector	1	1.000	-	-		otm25830
orthoMCL	1	0.900	-	-		OOG6_101382
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1015
SonicParanoid	1	1.000	-	-		X1020
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870