Protein Alignment Prosbeta2 and PSMA6

DIOPT Version :10

• Sequence 1: NP_524076.2
• Gene: Prosbeta2 / 39628
• FlyBaseID: FBgn0023174
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002782.1
• Gene: PSMA6 / 5687
• HGNCID: 9535
• Length: 246
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 49/259 - (18%)
• Similarity: 78/259 - (30%)
• Gaps: 107/259 - (41%)

  Fly    26 LNRGFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAAD 90
            :|:|         |.|.|.:..||..::....:..: .::.......:..:.:||.|...|..||
Human    32 INQG---------GLTSVAVRGKDCAVIVTQKKVPD-KLLDSSTVTHLFKITENIGCVMTGMTAD 86

  Fly    91 TEMTTDLISSQLELHRLQTDREVRVVAANTMLK-------QMLFRYQGHIS-------------A 135
            :              |.|..| .|..|||...|       .||.:....||             .
Human    87 S--------------RSQVQR-ARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGC 136

  Fly   136 ALVLGGVD-KTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIA 199
            .::|.|:| :.||.:|...|.|                    :...:|              |.|
Human   137 CMILIGIDEEQGPQVYKCDPAG--------------------YYCGFK--------------ATA 167

  Fly   200 SGVFNDLGSGSNIDLCVIRKGSVEYLRNYELANKKGKRQLDYRFK-------TGTSTVLHTNIK 256
            :|                    |:...:.....||.|::.|:.|:       |..||||..:.|
Human   168 AG--------------------VKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFK 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	proteasome_beta_type_7	42..228	CDD:239732	34/206 (17%)
		Pr_beta_C	231..264	CDD:463597	11/33 (33%)
PSMA6	NP_002782.1	proteasome_alpha_type_6	8..220	CDD:239723	49/259 (19%)