Protein Alignment Prosbeta2 and PSMA4

DIOPT Version :10

• Sequence 1: NP_524076.2
• Gene: Prosbeta2 / 39628
• FlyBaseID: FBgn0023174
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_002780.1
• Gene: PSMA4 / 5685
• HGNCID: 9533
• Length: 261
• Species: Homo sapiens
• Alignment Length: 224
• Identity: 52/224 - (23%)
• Similarity: 99/224 - (44%)
• Gaps: 32/224 - (14%)

  Fly    41 TIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISSQLELH 105
            |.:||:..|||:|.|:.|.....:.......||:.|.:::.|..||..:|..:.|:.:....:.:
Human    33 TCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRY 97

  Fly   106 RLQTDREV---RVVAANTMLKQMLFRYQGH--ISAALVLGGVDK-TGPHIYSIHPHGSSDKLPYA 164
            .||....:   ::|.|...:||...::.|.  ...:|:..|.|| .|..:|...|.|:.......
Human    98 LLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKAT 162

  Fly   165 TMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASG--VFN---DLG--SGSNIDLC------- 215
            .:|:.|.||:::.:..:|      ||:..::.|:|..  |.|   |:.  |...:::.
Human   163 CIGNNSAAAVSMLKQDYK------EGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENG 221

  Fly   216 -----VIRKGSVEYL-RNYELANKKGKRQ 238
                 |:::..||.| :.:|....|.:|:
Human   222 KTVIRVLKQKEVEQLIKKHEEEEAKAERE 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	proteasome_beta_type_7	42..228	CDD:239732	48/211 (23%)
		Pr_beta_C	231..264	CDD:463597	2/8 (25%)
PSMA4	NP_002780.1	proteasome_alpha_type_4	3..216	CDD:239721	45/188 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..261		3/11 (27%)