DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and Prosbeta7

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_649529.1	Gene:	Prosbeta7 / 40639	FlyBaseID:	FBgn0250746	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	232	Identity:	57/232 - (24%)
Similarity:	107/232 - (46%)	Gaps:	18/232 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PRAGFNFDNCKRNATLLNR--------GFKPPT-TTKTGTTIVGIIYKDGVILGADTRATEGPIV 65
            |...:||...:.....|.|        |.|..| ::.|||:::||.|..||:|.|||..:.|.:.
  Fly    19 PGEFYNFTGGQTPVQQLPRELTTMGPYGTKHSTASSTTGTSVLGIRYDSGVMLAADTLVSYGSMA 83

  Fly    66 SDKNCAKIHYLAKNIYCCGAGTAADTE-MTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRY 129
            ..:|..::..:.|||...|:|..||.: :..::....:|......:.|::..:..:.:.::|:..
  Fly    84 RYQNIERVFKVNKNILLGGSGDFADIQSIKRNIDQKMIEDQCCDDNIEMKPKSLASWMTRVLYNR 148

  Fly   130 QGHISAA---LVLGGVDKTG-PHIYSIHPHGSS-DKLPYATMGSGSLAAMTVFESRWKP-DLSEE 188
            :..::..   :|:||||..| |::.::...|.| :....||..:..||...|.|.:.|. |.:..
  Fly   149 RSRMNPLYIDVVVGGVDNEGTPYLANVDLRGRSYEDYVVATGFARHLAVPLVREKKPKDRDFTAV 213

  Fly   189 EGKKLVRDAIASGVFNDLGSGS--NIDLCVIRKGSVE 223
            |..:|:|..:....:.|..:.|  .:.:|.:....||
  Fly   214 EASELIRTCMEVLYYRDTRNISQYTVGVCSVNGCGVE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	46/191 (24%)
		proteasome_beta_type_7	42..228	CDD:239732	46/191 (24%)
		Pr_beta_C	232..264	CDD:289249
Prosbeta7	NP_649529.1	proteasome_beta_type_4	60..252	CDD:239729	46/191 (24%)
Prosbeta7	NP_649529.1	PRE1	60..232	CDD:223711	42/171 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940