DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and Prosbeta6

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_524115.1	Gene:	Prosbeta6 / 39855	FlyBaseID:	FBgn0002284	Length:	235	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	51/215 - (23%)
Similarity:	88/215 - (40%)	Gaps:	24/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GFKPPTTT---KTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCGAGTAAD 90
            |.|.|..:   ..|.:||.|...|..::.||||.:.|..:..:..:|:..|:.......||..||
  Fly    16 GMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWAD 80

  Fly    91 TEMTTDLISSQLELH-----RLQTDREVRVVAANTMLKQMLFRYQGHISAALVLGGVDKTGPH-I 149
            |...|..|..:::.:     |..|...|..:.:..|..:..|.|  ::|.  :|.|:|..|.. :
  Fly    81 TLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPY--YVSN--ILAGIDNEGKGVV 141

  Fly   150 YSIHPHGSSDKLPYATMGSGSLAAMTVFESRW-----------KPDLSEEEGKKLVRDAIASGVF 203
            ||..|.|..:|..|...|:.......|.:::.           |..|::|....:..|...|...
  Fly   142 YSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFISAAE 206

  Fly   204 NDLGSGSNIDLCVIRKGSVE 223
            .|:.:|.::.:.:|.|..:|
  Fly   207 RDIYTGDSVLINIITKDGIE 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	47/199 (24%)
		proteasome_beta_type_7	42..228	CDD:239732	47/199 (24%)
		Pr_beta_C	232..264	CDD:289249
Prosbeta6	NP_524115.1	proteasome_beta_type_1	22..235	CDD:239726	48/209 (23%)
Prosbeta6	NP_524115.1	PRE1	24..225	CDD:223711	47/204 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840