DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and Prosbeta5R1

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_611776.1	Gene:	Prosbeta5R1 / 37690	FlyBaseID:	FBgn0034842	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	57/179 - (31%)
Similarity:	89/179 - (49%)	Gaps:	5/179 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 GTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCG--AGTAADTEMTTDLISSQ 101
            |||.:|..|:.||||.||:|||.|..:..:...||..|  |.|..|  ||.|||......:::.:
  Fly    71 GTTTLGFKYRGGVILCADSRATSGQYIGSQTMRKIVEL--NDYMLGTLAGGAADCVYWDRVLAKE 133

  Fly   102 LELHRLQTDREVRVVAANTMLKQMLFRYQG-HISAALVLGGVDKTGPHIYSIHPHGSSDKLPYAT 165
            ..||:|:..:.:.|..|..::..:...|:| .:...::|.|.|..||.:..:...|........:
  Fly   134 CRLHQLRYRKRMTVDTAARIICNISTEYKGMGLVMGMMLAGFDDEGPKLIYVDSEGMRSHGQVFS 198

  Fly   166 MGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDL 214
            :||||..|:.|.::.::.|||::|...|.|.||......|..||..:.|
  Fly   199 VGSGSPYALGVLDTGYRYDLSDQEAYDLARRAIYHATSKDAYSGGIVRL 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	54/176 (31%)
		proteasome_beta_type_7	42..228	CDD:239732	54/176 (31%)
		Pr_beta_C	232..264	CDD:289249
Prosbeta5R1	NP_611776.1	PTZ00488	39..272	CDD:185666	57/179 (32%)
Prosbeta5R1	NP_611776.1	proteasome_beta_type_5	72..259	CDD:239730	56/178 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440969
Domainoid	1	1.000	44	1.000	Domainoid score	I729
eggNOG	1	0.900	-	-		E1_COG0638
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840