DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Prosbeta2 and Psmb7

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_035317.1	Gene:	Psmb7 / 19177	MGIID:	107637	Length:	277	Species:	Mus musculus

Alignment Length:	266	Identity:	174/266 - (65%)
Similarity:	208/266 - (78%)	Gaps:	15/266 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PRAGFNFDNCKRNATL----LNRGFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNC 70
            |..||:||||:|||.|    ..:|||.|...||||||.|::||||::||||||||||.:|:||||
Mouse    10 PVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGMVVADKNC 74

  Fly    71 AKIHYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISA 135
            :|||:::.|||||||||||||:|||.||||.||||.|.|.|..|||.||.|||||||||||:|.|
Mouse    75 SKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQGYIGA 139

  Fly   136 ALVLGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIAS 200
            ||||||||.||||:|||:||||:|||||.||||||||||.|||.:::||:.|||.||||.:|||:
Mouse   140 ALVLGGVDVTGPHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAA 204

  Fly   201 GVFNDLGSGSNIDLCVIRKGSVEYLRNYELANKKGKRQLDYRFKTGTSTVLHTNIKDLLVTERVQ 265
            |:|||||||||||||||.|..:::||.:.:.||||.|...||.:.||:.||         ||:|
Mouse   205 GIFNDLGSGSNIDLCVISKSKLDFLRPFSVPNKKGTRLGRYRCEKGTTAVL---------TEKV- 259

  Fly   266 AVPMEI 271
             .|:||
Mouse   260 -TPLEI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	137/189 (72%)
		proteasome_beta_type_7	42..228	CDD:239732	137/185 (74%)
		Pr_beta_C	232..264	CDD:289249	13/31 (42%)
Psmb7	NP_035317.1	PRE1	41..225	CDD:223711	140/183 (77%)
		proteasome_beta_type_7	44..232	CDD:239732	139/187 (74%)
		Pr_beta_C	236..271	CDD:289249	17/40 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	294	1.000	Domainoid score	I1487
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2093
Inparanoid	1	1.050	348	1.000	Inparanoid score	I2279
Isobase	1	0.950	-	0	Normalized mean entropy	S457
OMA	1	1.010	-	-		QHG53608
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001188
OrthoInspector	1	1.000	-	-		oto91943
orthoMCL	1	0.900	-	-		OOG6_101382
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1015
SonicParanoid	1	1.000	-	-		X1020
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.810