DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and Psmb5

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_035316.1	Gene:	Psmb5 / 19173	MGIID:	1194513	Length:	264	Species:	Mus musculus

Alignment Length:	184	Identity:	58/184 - (31%)
Similarity:	95/184 - (51%)	Gaps:	5/184 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 GTTIVGIIYKDGVILGADTRATEGPIVSDKNCAKIHYLAKNIYCCG--AGTAADTEMTTDLISSQ 101
            |||.:...:..|||:.||:|||.|..::.:...|:  :..|.|..|  ||.|||......|::.|
Mouse    59 GTTTLAFKFLHGVIVAADSRATAGAYIASQTVKKV--IEINPYLLGTMAGGAADCSFWERLLARQ 121

  Fly   102 LELHRLQTDREVRVVAANTMLKQMLFRYQG-HISAALVLGGVDKTGPHIYSIHPHGSSDKLPYAT 165
            ..::.|:....:.|.||:.:|..|:::|:| .:|...::.|.||.||.:|.:...|:.......:
Mouse   122 CRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGTAFS 186

  Fly   166 MGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRK 219
            :||||:.|..|.:..:..||..||...|.|.||....:.|..||..::|..:|:
Mouse   187 VGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHVRE 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	55/181 (30%)
		proteasome_beta_type_7	42..228	CDD:239732	55/181 (30%)
		Pr_beta_C	232..264	CDD:289249
Psmb5	NP_035316.1	proteasome_beta_type_5	60..247	CDD:239730	57/183 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810