DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and pbs-3

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_494913.1	Gene:	pbs-3 / 173858	WormBaseID:	WBGene00003949	Length:	204	Species:	Caenorhabditis elegans

Alignment Length:	190	Identity:	44/190 - (23%)
Similarity:	84/190 - (44%)	Gaps:	7/190 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 TGTTIVGIIYKDGVILGADTRATE--GPIVSDKNCAKIHYLAKNIYCCGAGTAADTEMTTDLISS 100
            ||.|:|.:...:.|.:.:|.|..|  ..|.:|:.  |:|.:...:|...||..:|.....:.|..
Worm     7 TGGTVVAMAGDECVCIASDLRIGEQMTTIATDQK--KVHKVTDKVYVGLAGFQSDARTVLEKIMF 69

  Fly   101 QLELHRLQTDREVRVVAANTMLKQMLF--RYQGHISAALVLGGVDKTGPHIYSIHPHGS-SDKLP 162
            :..|:.|:.:|.::....:.|:..:.:  |:..:.:..||.|..|...|:|..:...|. |....
Worm    70 RKNLYELRENRNIKPQVLSEMISNLAYQHRFGSYFTEPLVAGLDDTNKPYICCMDTIGCVSAPRD 134

  Fly   163 YATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASGVFNDLGSGSNIDLCVIRKGSV 222
            :..:|:|....:.|.|:.|:.::..:|..:....:|.|.:..|..||....:..|.|..|
Worm   135 FVAVGTGQEYLLGVCENFWRENMKPDELFEATAQSILSCLERDAASGWGAVVYTITKDKV 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	41/186 (22%)
		proteasome_beta_type_7	42..228	CDD:239732	41/186 (22%)
		Pr_beta_C	232..264	CDD:289249
pbs-3	NP_494913.1	PRE1	3..193	CDD:223711	43/187 (23%)
pbs-3	NP_494913.1	proteasome_beta_type_3	6..200	CDD:239728	44/190 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810