DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosbeta2 and pbs-2

DIOPT Version :9

Sequence 1:	NP_524076.2	Gene:	Prosbeta2 / 39628	FlyBaseID:	FBgn0023174	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_493271.1	Gene:	pbs-2 / 173168	WormBaseID:	WBGene00003948	Length:	277	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	109/259 - (42%)
Similarity:	160/259 - (61%)	Gaps:	16/259 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DLPRAG-FNFDNCKRNATLLNRGFKPPTTTKTGTTIVGIIYKDGVILGADTRATEGPIVSDKNCA 71
            |:.|.| |:|.||.||..:...|.|.|..|.||||||.:.:|.|:::|||:|||.|.|::||:|.
Worm    14 DMDRGGAFDFSNCIRNQAMCKMGGKAPKLTSTGTTIVAVAFKGGLVMGADSRATAGNIIADKHCE 78

  Fly    72 KIHYLAKNIYCCGAGTAADTEMTTDLISSQLELHRLQTDREVRVVAANTMLKQMLFRYQGHISAA 136
            |:|.|.::||.||||||||.:..|.::|..|.|..|.|.|:.||:.|....||.||.|||:|.|.
Worm    79 KVHKLTESIYACGAGTAADLDQVTKMLSGNLRLLELNTGRKARVITALRQAKQHLFNYQGYIGAY 143

  Fly   137 LVLGGVDKTGPHIYSIHPHGSSDKLPYATMGSGSLAAMTVFESRWKPDLSEEEGKKLVRDAIASG 201
            |::||||.||||:|....:|::...|:...||||.||:|:.|..:|.|::::|.:|||:.|:.:|
Worm   144 LLIGGVDPTGPHLYMCSANGTTMAFPFTAQGSGSYAAITILERDFKVDMTKDEAEKLVQRALEAG 208

  Fly   202 VFNDLGSGSNIDLCVIR------KGSV--EYLRNYELANKKGKRQLDYRFKTGTSTVL-HTNIK 256
            :..|..||::::|.:|.      ||.:  |:.:..|      ...|.|:|:.|.:.|| |...|
Worm   209 MHGDNASGNSLNLVIIEPSETVFKGPIVPEFCKRPE------PNDLVYKFQAGATKVLKHKTYK 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosbeta2	NP_524076.2	PRE1	42..232	CDD:223711	84/197 (43%)
		proteasome_beta_type_7	42..228	CDD:239732	83/193 (43%)
		Pr_beta_C	232..264	CDD:289249	8/26 (31%)
pbs-2	NP_493271.1	PRE1	43..228	CDD:223711	85/184 (46%)
pbs-2	NP_493271.1	proteasome_beta_type_7	47..235	CDD:239732	84/187 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157341
Domainoid	1	1.000	182	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I2377
Isobase	1	0.950	-	0	Normalized mean entropy	S457
OMA	1	1.010	-	-		QHG53608
OrthoDB	1	1.010	-	-		D415498at33208
OrthoFinder	1	1.000	-	-		FOG0001188
OrthoInspector	1	1.000	-	-		otm14620
orthoMCL	1	0.900	-	-		OOG6_101382
Panther	1	1.100	-	-	LDO	PTHR11599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1015
SonicParanoid	1	1.000	-	-		X1020
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.750