Protein Alignment Zip71B and slc39a10

DIOPT Version :9

• Sequence 1: NP_001097608.1
• Gene: Zip71B / 39626
• FlyBaseID: FBgn0036461
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: XP_005167603.1
• Gene: slc39a10 / 393644
• ZFINID: ZDB-GENE-040426-1157
• Length: 891
• Species: Danio rerio
• Alignment Length: 815
• Identity: 203/815 - (24%)
• Similarity: 315/815 - (38%)
• Gaps: 322/815 - (39%)

  Fly    23 PASTEYNKYVAQIFQKYGNGGTINFEGLEHLMFSLNLGQIQF----------------------D 65
            ||..|...|:.|:|.:||....::|:|.:.|:.||.||:::.                      |
Zfish   115 PAENEQRYYIHQLFCRYGQKDRLDFKGFQSLLLSLGLGEVRVVGLEHEDLGHDHVAHLDILEVQD 179

  Fly    66 PSHTIDQHRPQGYSN-EMPHATNVTYYFE---------------------PTRVNA--------- 99
            ..|:.....|..:.| .:.|.|:...:.|                     |..|:.
Zfish   180 GRHSHSAGHPHSHQNPNISHKTHQHSHHENEEHTLAEDVPCSKTLGTGATPPSVSEEHDHDHEHD 244

  Fly   100 ------TDEEALELQI--SPR-----------GNHSNSQSEAEVPEFLEI-HDPK---------- 134
                  :|.|.....:  ||:           ..||:.| :::|.:.||: ||.|
Zfish   245 HDHDKDSDHEHNHRHVTDSPQTQDHEHDHIHLHTHSHKQ-DSDVTQRLELDHDQKSREHAQEHND 308

  Fly   135 -------------HRHPR---ESSEPVAACLS--PKSLLS----LIVNHNDLHKNIAYRKL---- 173
                         |:||.   .:.|.|....|  ||...|    |..|....|:..:..|.
Zfish   309 LSDQNHHHHDHHHHKHPHPHLHAPESVVHTTSAMPKIQPSVPPELPANQTRRHRRPSKVKAHRGR 373

  Fly   174 ---------LIKNDVSSTDGVHNSEE-----------------------EYNEFINSVR------ 200
                     .::.:.|..|..|:.::                       ::.|.:|..:
Zfish   374 NRTSVTVTQAVELETSGDDHEHSLQDHSPAQQQRGRREVPGSPAHGVLHQHEECLNLTQLLHQYG 438

  Fly   201 ------ITPRAFMKLCPALLAQIDNGVC----------KQPAVRSVNLNDKNQKIWYAWIYASIT 249
                  |:|..|..||||||.|||...|          :|.|..|          .:.|::..::
Zfish   439 LSSDSLISPVQFTYLCPALLYQIDRRFCILHYHHVEAEEQVAPSS----------GWVWMWGFVS 493

  Fly   250 MLILSACGLLGILLVPLMKSAAYQEILKFLVSIAVGTLAGDALMHLLPHA--------------- 299
            :.|:|...|||::|||::..:.::.:|.|||::|||||:||||:|||||:
Zfish   494 ITIISLLSLLGVVLVPILNQSCFKFLLTFLVALAVGTLSGDALLHLLPHSQGDHDHNHGEQMEEE 558

  Fly   300 ------------------------LF---------------------KEEKHEE----------- 308
                                    ||                     |::|.|:
Zfish   559 PEVDFLIKFDGVWKGLTALAGIYLLFIIEHCIGMFKHYSDQRGGLCHKKKKGEQAKIGRKLSDHK 623

  Fly   309 ------------------------------EVTGINPLE---------SDHKHSNEAALLCGCTF 334
                                          ::|.:.||:         ||..|..||.:...
Zfish   624 LNRRSDAEWLHLKPLTEGDGTTCEAGHNDTQMTELQPLDSPSKMPLNISDSDHPYEAPVKTE--- 685

  Fly   335 LAALFMYMLENLIPLLKGGKPGHGHSHGHGHSHGRS-HGHMEKPAAKDAIDLPPPRELNVMLQEA 398
                     |:.:|..|..|.||||.|||||.||.| |||...
Zfish   686 ---------EDNVPKAKSKKHGHGHGHGHGHGHGHSHHGHCHS---------------------- 719

  Fly   399 KLDEKTPDRPLTPVAFMVIIGDGLHNLTDGLAIGAAFASDPVTGFATAFAVLCHELPHELGDFAL 463
              |::..|..:..:|:|||:|||:||.:|||||||||:::...|.:|:.||.||||||||||||:
Zfish   720 --DQEMKDAGIASIAWMVIMGDGMHNFSDGLAIGAAFSANITGGISTSVAVFCHELPHELGDFAV 782

  Fly   464 LLQTGVSMRRAVYMNIVSSVLSFVGMSVGLFIAGIGDGMTQWIYAATAGSFLYIAFADLVPTMSV 528
            ||:.|:|:::|:..|::|:::::.||.:|..:......:|.||:|.|||.|||:|..|::|.|..
Zfish   783 LLKAGMSVKQAIVYNLLSALMAYAGMVIGTAVGQYTHNVTSWIFAVTAGMFLYVALVDMLPEMLH 847

  Fly   529 AHNPEKAKDPKG-IIIQIFGILLGGLIMLAIALNE 562
            ..:.|..:...| .::|.||:|.|..|||.||:.|
Zfish   848 GDSEEHKRCEMGHFVLQNFGMLTGFGIMLLIAIFE 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zip71B	NP_001097608.1	Zip	242..559	CDD:280666	129/428 (30%)
slc39a10	XP_005167603.1	Zip	515..879	CDD:280666	120/399 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	220	1.000	Domainoid score	I2562
eggNOG	1	0.900	-	-		E1_COG0428
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D461652at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12191
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4006
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.910