Protein Alignment mnd and CAN1

DIOPT Version :9

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_010851.1
• Gene: CAN1 / 856646
• SGDID: S000000789
• Length: 590
• Species: Saccharomyces cerevisiae
• Alignment Length: 560
• Identity: 116/560 - (20%)
• Similarity: 202/560 - (36%)
• Gaps: 186/560 - (33%)

  Fly     5 QASDSLIPRQVFEVPPAEPNNSTADSGSQGSG---------VKLKKQ-----IGLLDGVAIIVGV 55
            :.|..|.|.:.|   |...|.....|...|.|         .::|::     ||:     |.:|.
Yeast    44 EKSKELYPLRSF---PTRVNGEDTFSMEDGIGDEDEGEVQNAEVKRELKQRHIGM-----IALGG 100

  Fly    56 IVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGG----DYAYIGTA 116
            .:|:|:|:.....|..:|.:| :||.::..|.|:........|:.|.||.:..    ...::..|
Yeast   101 TIGTGLFIGLSTPLTNAGPVG-ALISYLFMGSLAYSVTQSLGEMATFIPVTSSFTVFSQRFLSPA 164

  Fly   117 FGPLPAFLYLWVALLILVPTGNAITALTFAIYL-----LKPFWPSCDAPIEAVQLLAAAMI---- 172
            ||....::| |.:           .|:|||:.|     :..|| :...|:       ||.|
Yeast   165 FGAANGYMY-WFS-----------WAITFALELSVVGQVIQFW-TYKVPL-------AAWISIFW 209

  Fly   173 CVLTLINCYNVK-------WVTRVTDIFTGTKVVALL--------VIVGAGVWWLFDG--NTEHW 220
            .::|::|.:.||       ||..:       ||:|::        ::.||||    .|  ...:|
Yeast   210 VIITIMNLFPVKYYGEFEFWVASI-------KVLAIIGFLIYCFCMVCGAGV----TGPVGFRYW 263

  Fly   221 DNPFSGGLQDPGYIA--------LAFYSGL----FSYSGWNYLNFVTEELKDPYRNLPKAI-CIS 272
            .||   |...||.|:        |.:.|.|    |::.|...:.....|..:|.:::|:|| .:.
Yeast   264 RNP---GAWGPGIISKDKNEGRFLGWVSSLINAAFTFQGTELVGITAGEAANPRKSVPRAIKKVV 325

  Fly   273 MPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKML----GYMSWIMPFAVACSTFG----- 328
            ..::|  :.|.::.:..:|.|            :.|..|    .|:| ..||.:|....|
Yeast   326 FRILT--FYIGSLLFIGLLVP------------YNDPKLTQSTSYVS-TSPFIIAIENSGTKVLP 375

  Fly   329 -------------SLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLF 380
                         :.|..|:..||:.|..::|...|..:|...            .|.:..:.:|
Yeast   376 HIFNAVILTTIISAANSNIYVGSRILFGLSKNKLAPKFLSRTT------------KGGVPYIAVF 428

  Fly   381 IEDVYVLINYV-------SYVEALFTLISVSGLL-WM-------RYKQ-------PKTERPIKVN 423
            :...:..:.|:       ...|.|..:..|:|.. |:       |:.|       .:.|.|.|..
Yeast   429 VTAAFGALAYMETSTGGDKVFEWLLNITGVAGFFAWLFISISHIRFMQALKYRGISRDELPFKAK 493

  Fly   424 LALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVY 463
            | :|.:......|:.|              |||:.|...:
Yeast   494 L-MPGLAYYAATFMTI--------------IIIIQGFTAF 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	111/543 (20%)
CAN1	NP_010851.1	2A0310	85..562	CDD:273334	107/516 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345704
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940