Protein Alignment mnd and LYP1

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_014131.1
• Gene: LYP1 / 855453
• SGDID: S000005212
• Length: 611
• Species: Saccharomyces cerevisiae
• Alignment Length: 615
• Identity: 129/615 - (20%)
• Similarity: 219/615 - (35%)
• Gaps: 185/615 - (30%)

  Fly    17 EVPPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAII----------------------------- 52
            |:...:|:|.|............||:.|.|.|.||.
Yeast    36 EMEAIDPSNKTTPYSIDEKQYNTKKKHGSLQGGAIADVNSITNSLTRLQVVSHETDINEDEEEAH 100

  Fly    53 --------------VGVI-----VGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAE 98
                          :|:|     :|:|:||.....|..:|.:| |||.::..|.:.........|
Yeast   101 YEDKHVKRALKQRHIGMIALGGTIGTGLFVGISTPLSNAGPVG-SLIAYIFMGTIVYFVTQSLGE 164

  Fly    99 LGTMIPKSGG----DYAYIGTAFGPLPAFLYL--WVALLILVPTGNAITALTFAIYL-----LKP 152
            :.|.||.:..    ...::..|||....::|.  |              |:|:|:.:     :..
Yeast   165 MATFIPVTSSITVFSKRFLSPAFGVSNGYMYWFNW--------------AITYAVEVSVIGQVIE 215

  Fly   153 FWPSCDAPIEAVQLLA--AAMICVLTLINCYNVK-------WVTRVTDI-FTGTKVVALLVIVGA 207
            :|      .:.|.|.|  |....::||:|.:.||       ||..|..: ..|..:.||:::.|.
Yeast   216 YW------TDKVPLAAWIAIFWVIITLMNFFPVKVYGEFEFWVASVKVLAIMGYLIYALIIVCGG 274

  Fly   208 GVWWLFDG--NTEHWDNPFSGGLQDPGYIA--------LAFYSGL----FSYSGWNYLNFVTEEL 258
            .    ..|  ...:|.||   |...||.|:        |.:.|.|    |:|.|...:.....|.
Yeast   275 S----HQGPIGFRYWRNP---GAWGPGIISSDKSEGRFLGWVSSLINAAFTYQGTELVGITAGEA 332

  Fly   259 KDPYRNLPKAICISMPVV--TVIYMITNIAYFSVLSP--DEILSSDAVAVTFGDKMLGYM---SW 316
            .:|.:.:|:||   ..||  .|::.|.::.:..:|.|  |..||:.:..:.....::...   ::
Yeast   333 ANPRKTVPRAI---NKVVFRIVLFYIMSLFFIGLLVPYNDSRLSASSAVIASSPFVISIQNAGTY 394

  Fly   317 IMP----FAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLL 377
            .:|    ..|..:...:.|..::..||:.:..||.|:.|.....:.   ...||   :|||:...
Yeast   395 ALPDIFNAVVLITVVSAANSNVYVGSRVLYSLARTGNAPKQFGYVT---RQGVP---YLGVVCTA 453

  Fly   378 LLFIEDVYVLINYVSYVEALFTLISVSGL----LWM-------RYKQPKTER-------PIKVNL 424
            .|.:....|:.|..:  .|...||::|.|    .|:       |:.|....|       |.|..|
Yeast   454 ALGLLAFLVVNNNAN--TAFNWLINISTLAGLCAWLFISLAHIRFMQALKHRGISRDDLPFKAKL 516

  Fly   425 ALP------IIYLIVCLFLVIFS--CT------QTPYVVGIGTIIILSGIPVYY----------L 465
             :|      ..::.|.:|:..|.  |.      .|.|:..|...::..|..:||          :
Yeast   517 -MPYGAYYAAFFVTVIIFIQGFQAFCPFKVSEFFTSYISLILLAVVFIGCQIYYKCRFIWKLEDI 580

  Fly   466 TIH------KPVKWLADTSQAINLWCSKFF 489
            .|.      :.:.|..|..:  ||| .||:
Yeast   581 DIDSDRREIEAIIWEDDEPK--NLW-EKFW 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	128/610 (21%)
LYP1	NP_014131.1	2A0310	107..583	CDD:273334	110/515 (21%)