Protein Alignment mnd and SLC7A5

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_003477.4
• Gene: SLC7A5 / 8140
• HGNCID: 11063
• Length: 507
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 253/500 - (50%)
• Similarity: 343/500 - (68%)
• Gaps: 18/500 - (3%)

  Fly    13 RQVFEVPPAEPNN---------STADSGS---QGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSP 65
            |:....|.||...         .:||..:   :|.||.|::.|.||:|||||||.|:||||||:|
Human     8 RRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTP 72

  Fly    66 KGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVAL 130
            .||||.:||.|.:|:||...||.|:|||||||||||.|.||||||||:...:|.|||||.||:.|
Human    73 TGVLKEAGSPGLALVVWAACGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIEL 137

  Fly   131 LILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTG 195
            ||:.|:...|.||.||.|||||.:|:|..|.||.:|:|...:.:||.:|||:||..|||.|.|..
Human   138 LIIRPSSQYIVALVFATYLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAA 202

  Fly   196 TKVVALLVIVGAGVWWLFDGNTEHWDNPFS--GGLQDPGYIALAFYSGLFSYSGWNYLNFVTEEL 258
            .|::||.:|:..|...:..|:..:.|..||  |...|.|.|.||.|||||:|.|||||||||||:
Human   203 AKLLALALIILLGFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEM 267

  Fly   259 KDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVA 323
            .:||||||.||.||:|:||::|::||:|||:.||.:::|||:||||.||:..||.||||:|..|.
Human   268 INPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVG 332

  Fly   324 CSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLI 388
            .|.|||:||::|.||||||||:|.||||:.:|:|:...|||||||:|..|:|||..|.:|::.:|
Human   333 LSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIFSVI 397

  Fly   389 NYVSYVEALFTLISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGT 453
            |:.|:...|...:::.|::|:|:::|:.|||||||||||:.:::.||||:..|..:||...|||.
Human   398 NFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKTPVECGIGF 462

  Fly   454 IIILSGIPVYYLTI---HKPVKWLADTSQAINLWCSKFFICMPNQ 495
            .|||||:|||:..:   :|| |||.....:..:.|.|....:|.:
Human   463 TIILSGLPVYFFGVWWKNKP-KWLLQGIFSTTVLCQKLMQVVPQE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	250/490 (51%)
SLC7A5	NP_003477.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		6/31 (19%)
		2A0308	26..506	CDD:273332	249/480 (52%)