DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and LOC688389

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	XP_001066729.3	Gene:	LOC688389 / 688389	RGDID:	1589989	Length:	469	Species:	Rattus norvegicus

Alignment Length:	470	Identity:	137/470 - (29%)
Similarity:	248/470 - (52%)	Gaps:	17/470 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 VKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSG-SIGQSLIVWVLSGVLSMVGALCYAELG 100
            ::|.:.:|......:::|.|:|:|||||||||||:|. :|..||.:|...|:|.|:.||...||.
  Rat     1 MRLSRTVGFFHVTMVLLGTIIGTGIFVSPKGVLKYSSLNIPVSLGIWAGCGLLVMLNALSLVELA 65

  Fly   101 TMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQ 165
            |..|.||..|.::..:.|.|.|||.||:.|.... .|.....|..|.||::||:..|.||...::
  Rat    66 TTFPVSGASYYFLKRSLGSLAAFLSLWIQLFSYC-LGLGAHTLLIATYLIQPFYTGCPAPELPIK 129

  Fly   166 LLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDG---NTEHWDNPFSGG 227
            .|:.|::....::|...||.|..:..|.:..|:..|..|...|:..|..|   |...::|.....
  Rat   130 CLSVAILWSFGILNAGGVKTVAWLQTISSMIKMSILCFISLTGLVLLVIGKKENVSKFENALDAE 194

  Fly   228 LQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAI--CISMPVVTVIYMITNIAYFSV 290
            |.:......|...|.|:|.|...:..:..|:|:|.:.:|||:  |:|:.:::  |::.|:||.:|
  Rat   195 LPNASQTVEAILQGCFAYRGIFIVINIAGEIKNPSKIIPKAVISCLSITIMS--YLLANVAYLTV 257

  Fly   291 LSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAIS 355
            |:|.||.:||:|.:|:.::....|.|:|...::.|:..:....|.:::|:.:..:..|.:|...|
  Rat   258 LTPKEITTSDSVVITWVNRAYPSMQWVMSLGISLSSLTTTACGILSAARICYSASLEGQMPFIFS 322

  Fly   356 LINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPKTERPI 420
            ::| |..:||.::..:.:|:.:.:...::..||.|:..:.....::.:..:|.:||::|...||.
  Rat   323 MLN-NHQSPVVAVTQVVILSTVSIICSNLTYLIKYLGIMSIFNDVLYMIAILKLRYQKPALPRPY 386

  Fly   421 KVNLALPIIY--LIVCLFLVIFSCTQTPYVVGI-GTIIILSGIPVYYLTIHKPVKWLADTSQAIN 482
            ||  .||:::  |.:..|.::....|:|.:..| ..:.:|||..||:|.::  :...||..:.|.
  Rat   387 KV--CLPLVFGSLALSSFFILAPIIQSPNIEHIYEGLFLLSGFVVYWLQVY--LYQHADHFKTIT 447

  Fly   483 LWCSKFFICMPNQEK 497
            .:....|..:|:.|:
  Rat   448 CYLQLLFNVLPSDEQ 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	136/467 (29%)
LOC688389	XP_001066729.3	PotE	1..437	CDD:223605	131/443 (30%)
LOC688389	XP_001066729.3	SLC5-6-like_sbd	5..>266	CDD:294310	88/263 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351236
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750