Protein Alignment mnd and SLC7A4

DIOPT Version :9

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_004164.2
• Gene: SLC7A4 / 6545
• HGNCID: 11062
• Length: 635
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 105/456 - (23%)
• Similarity: 202/456 - (44%)
• Gaps: 70/456 - (15%)

  Fly     6 ASDSLIPRQVFEVPPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLK 70
            ||.:.:.:::..:.|.|  :||.::       .|::.:..||...:.||.:||||::|
Human     9 ASLARLCQKLNRLKPLE--DSTMET-------SLRRCLSTLDLTLLGVGGMVGSGLYV------- 57

  Fly    71 FSGSIGQS------LIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVA 129
            .:|::.:.      |:.:.::.|.|::.||||||.|..:|::|..|.:...:.|.|.|||..|..
Human    58 LTGAVAKEVAGPAVLLSFGVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGWNV 122

  Fly   130 LLILVPTGNAITALTFAIYLLKPF--------------WPSCDAPI--EAVQLLAAAMICVLT-L 177
            ||..: .|.|..|..::.||...|              |   ..|:  .....|||.:|.:.: .
Human   123 LLEYI-IGGAAVARAWSGYLDSMFSHSIRNFTETHVGSW---QVPLLGHYPDFLAAGIILLASAF 183

  Fly   178 INCYNVKWVTRVTDIFTGT-KVVALLVIVGAGVWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSG 241
            ::|     ..||:.....| ..::||||:...:.........:|.       .|.|..|...:||
Human   184 VSC-----GARVSSWLNHTFSAISLLVILFIVILGFILAQPHNWS-------ADEGGFAPFGFSG 236

  Fly   242 L--------FSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILS 298
            :        :::.|::.:...:||.::|.|::|.||.||:.:....|::.: ...:::.|...|.
Human   237 VMAGTASCFYAFVGFDVIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVS-TVLTLMVPWHSLD 300

  Fly   299 SD-AVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCL 362
            .| |:|..|..:...:..:|:.....|:....|...:|:..|:.:..|.:|......:.::....
Human   301 PDSALADAFYQRGYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQ 365

  Fly   363 TPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEAL-FTLISVSGLLWMRYKQPKTERPIKVNLAL 426
            .||...:..|:||..|..:.|:..|:.::|....| :|.::.| ::.:|::  |:..|.....|.
Human   366 VPVAGTLAFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATS-IIVLRFQ--KSSPPSSPGPAS 427

  Fly   427 P 427
            |
Human   428 P 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	102/440 (23%)
SLC7A4	NP_004164.2	2A0303	26..592	CDD:273330	101/437 (23%)
		AA_permease_C	540..590	CDD:290617

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157271
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850