Protein Alignment mnd and SLC7A1

DIOPT Version :9

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_016876202.1
• Gene: SLC7A1 / 6541
• HGNCID: 11057
• Length: 643
• Species: Homo sapiens
• Alignment Length: 570
• Identity: 118/570 - (20%)
• Similarity: 219/570 - (38%)
• Gaps: 153/570 - (26%)

  Fly    38 KLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIV-WVLSGVLSMVGALCYAELGT 101
            :|.:.:...|.||:.||..:|:|::|....|.:  .:.|.:::: ::::.:.|::..|||.|.|.
Human    27 RLSRCLNTFDLVALGVGSTLGAGVYVLAGAVAR--ENAGPAIVISFLIAALASVLAGLCYGEFGA 89

  Fly   102 MIPKSGGDYAYIGTAFGPLPAFLYLW-VALLILVPTGNAITA--LTFAIYLLKPFWP------SC 157
            .:||:|..|.|.....|.|.||:..| :.|..::.|.:...|  .||...:.:|...      :.
Human    90 RVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPIGEFSRTHMTL 154

  Fly   158 DAP---IEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEH 219
            :||   .|...:.|..:|.:||.:....||....|..|||...|:.|..|:.:|   ...|:.::
Human   155 NAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGFIMVSG---FVKGSVKN 216

  Fly   220 WD----------------------NPFSGGLQDPGY------IALAFYSGLFSYSGWNYLNFVTE 256
            |.                      .|..||....|:      .|..||    ::.|::.:....|
Human   217 WQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATCFY----AFVGFDCIATTGE 277

  Fly   257 ELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGY-------- 313
            |:|:|.:.:|..|..|:       :|..||||.|          :.|:|.   |:.|
Human   278 EVKNPQKAIPVGIVASL-------LICFIAYFGV----------SAALTL---MMPYFCLDNNSP 322

  Fly   314 -------MSWI-MPFAVA----CSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVP 366
                   :.|. ..:|||    |:...||.|::|...|:.:..|.:|.|...::.:|....||:.
Human   323 LPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPII 387

  Fly   367 SLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYK------------------- 412
            :.:..|.:..::.|:.|:..|::.:|....|...:..:.:|.:||:
Human   388 ATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMASTSDELDP 452

  Fly   413 -----------------------------QPKTERPIK-----VNLALPIIYLIVCLFLVIFSCT 443
                                         .||...|.|     ||::..:|.:::..|.::....
Human   453 ADQNELASTNDSQLGFLPEAEMFSLKTILSPKNMEPSKISGLIVNISTSLIAVLIITFCIVTVLG 517

  Fly   444 QTPYVVG-IGTIIILSGIPVYYLTIHKPVKWLADTSQA--------INLW 484
            :.....| :..:.:|:|..:....: ..|.|....|:.        :|.|
Human   518 REALTKGALWAVFLLAGSALLCAVV-TGVIWRQPESKTKLSFKTVLLNYW 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	118/570 (21%)
SLC7A1	XP_016876202.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157290
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850