DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and slc7a7

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001032648.1	Gene:	slc7a7 / 641560	ZFINID:	ZDB-GENE-051127-5	Length:	501	Species:	Danio rerio

Alignment Length:	500	Identity:	250/500 - (50%)
Similarity:	339/500 - (67%)	Gaps:	18/500 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SLIPRQVFEVPPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSG 73
            |..|....|..|...|.:...|.||.| :||||:|.||:||.:|||.::||||||||||||.:||
Zfish     3 SYSPTPAEEASPEVSNGNLKASSSQES-MKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSG 66

  Fly    74 SIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGN 138
            |.|.||:||.:.|:.|:.||||||||||.|.|||..||||..|||...||:.||.:|||:.||..
Zfish    67 SYGLSLVVWTIGGIFSVFGALCYAELGTTITKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQ 131

  Fly   139 AITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLV 203
            |:.|:||:.|:::|.:|:|.||..|.:|||||.||:||.:||..||:.|||.|.||..|||||:.
Zfish   132 AVIAITFSNYMVQPIFPTCIAPYVANRLLAAACICLLTFVNCAYVKYGTRVQDFFTYVKVVALIA 196

  Fly   204 IVGAGVWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKA 268
            ::..|:..:|.|.|::::..||....|||.:|||.||.|||||||:.|||||||:|:|.||||.|
Zfish   197 VIITGLVKIFQGYTQNFEGLFSDSSHDPGDVALALYSALFSYSGWDTLNFVTEEIKNPERNLPLA 261

  Fly   269 ICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGA 333
            |.||||:|||||::||:||:::|....||.||||||||.|::.||::|.:|.|||.|.||.||.:
Zfish   262 IAISMPIVTVIYILTNLAYYTILPIPAILDSDAVAVTFADQVFGYLNWTIPVAVAFSCFGGLNAS 326

  Fly   334 IFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALF 398
            |.|:|||||||:|.||||..:.:|::...||:|:|:|.|.:.|:.|.:|||:.||||.|:....|
Zfish   327 IVAASRLFFVGSREGHLPDYLCMIHITRFTPIPALLFNGAMALVYLCVEDVFKLINYYSFSYWFF 391

  Fly   399 TLISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVI---FSCTQTPYVVGIGTIIILSGI 460
            ..:|:.|.|::|:|||...||:|::|..|||:.:..:|||:   :|.|... ::|||  |.|.|:
Zfish   392 VGLSILGQLYLRWKQPDRPRPLKLSLFFPIIFCLCTVFLVVVPLYSDTINS-LIGIG--IALPGV 453

  Fly   461 PVYYLTIHKPV--------KWLADTSQAINLWCSKFFICMPNQEK 497
            |||:|..|.|.        |::|.:...|...|   |..:...:|
Zfish   454 PVYFLCCHLPATRRPMWLRKFIASSGVLIQKVC---FCVLTEMDK 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	245/484 (51%)
slc7a7	NP_001032648.1	2A0308	2..492	CDD:273332	249/495 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592984
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H88701
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.760