DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and slc7a10a

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001373301.1	Gene:	slc7a10a / 567420	ZFINID:	ZDB-GENE-080116-1	Length:	511	Species:	Danio rerio

Alignment Length:	482	Identity:	231/482 - (47%)
Similarity:	330/482 - (68%)	Gaps:	18/482 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DSGSQGSG----VKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLS 89
            ||....||    |.|||:||||...|||:|.|:|||||:||||||..:||:|.|||||||.|.:.
Zfish    21 DSRGNQSGSKDRVTLKKEIGLLSACAIIIGNIIGSGIFISPKGVLDHAGSVGFSLIVWVLGGGIC 85

  Fly    90 MVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFW 154
            .:|:|||||||..||||||||:|:...||.|..||.||.|:||:.||..|:.||||:.|:|:|.:
Zfish    86 ALGSLCYAELGVTIPKSGGDYSYVTEIFGGLVGFLLLWSAVLIMYPTTLAVIALTFSNYVLQPAF 150

  Fly   155 PSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEH 219
            |:|..|..|.:||:...:..||.:||.:|:|.||:.|:||..|::||::|:..|:..:..|   |
Zfish   151 PNCLPPYIATRLLSTTCVLFLTWVNCSSVRWGTRIQDVFTVGKLLALVLIIVVGMVQIAKG---H 212

  Fly   220 WD--NPFSG--GLQDP--GYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTV 278
            :|  .|.:.  .::||  |.|||||....|:|||||:||:||||:.:|.:|||:||.||:|:||:
Zfish   213 YDALEPQAAFEFIKDPSVGQIALAFLQASFAYSGWNFLNYVTEEVVEPRKNLPRAIYISIPLVTL 277

  Fly   279 IYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFV 343
            :|.:|||||||.:||.|:|.|:|||||||:|:||..||:||.:||.||||.:||.:|.||||.|.
Zfish   278 VYTLTNIAYFSSMSPQELLESNAVAVTFGEKLLGMFSWVMPISVALSTFGGINGYLFTSSRLCFS 342

  Fly   344 GARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLW 408
            |||.||||..:::|::...||:|:||.....|:::|.|.|.:.||||||::..|...::::|||:
Zfish   343 GAREGHLPYLLAMIHLKSCTPIPALIVCCTATIVILCIGDTHNLINYVSFINYLSYGVTIAGLLY 407

  Fly   409 MRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVYYLTI---HKP 470
            .|:|:|...|||||||.:|..||:....|:.||....|.|.|:|.:|:|:|:|:|::.:   :||
Zfish   408 YRWKKPNMFRPIKVNLLVPCSYLVFWAVLLGFSLYSEPVVCGMGLVIMLTGVPIYFIGVQWKNKP 472

  Fly   471 VKWLADTSQAINLWCSKF-FICMPNQE 496
             :|:....:.:.....|. ::..|..:
Zfish   473 -QWIYSAIERVTYLGQKMCYVVFPQDD 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	231/480 (48%)
slc7a10a	NP_001373301.1	2A0308	1..497	CDD:273332	231/479 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592993
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	448	1.000	Inparanoid score	I1598
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.700