DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and si:dkeyp-120h9.1

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001093492.1	Gene:	si:dkeyp-120h9.1 / 566469	ZFINID:	ZDB-GENE-070705-534	Length:	487	Species:	Danio rerio

Alignment Length:	467	Identity:	226/467 - (48%)
Similarity:	319/467 - (68%)	Gaps:	5/467 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGA 93
            ||||. |.::||::|.||.||.:|||.::||||||||.|||:.:||.|.||:||.:.|:.|:.||
Zfish     3 DSGST-SSMRLKQEISLLHGVCLIVGNMIGSGIFVSPIGVLEKTGSYGLSLVVWAIGGIFSVFGA 66

  Fly    94 LCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCD 158
            ||||||||.|.|||..||||...||...||:.||.:|:|:.|...|:.|||||.||:|||:|:|.
Zfish    67 LCYAELGTTIRKSGASYAYILETFGGFLAFIRLWTSLMIVEPACQAVIALTFANYLVKPFFPTCP 131

  Fly   159 APIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEHWDNP 223
            ||.:||:|:||.:|.:||::||..|||...:..|.|..||:||:||:.||:..|..|.|.::.:.
Zfish   132 APYDAVRLIAALIIGLLTIVNCMKVKWGAILQVISTVAKVLALIVIIIAGMVVLAQGETNNFRDS 196

  Fly   224 FSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYF 288
            |.....|||.::||.|:.|:|||||:.|||:|||:|:|.||||.:|.||||:||:||::||:||:
Zfish   197 FENSKLDPGNMSLALYAALYSYSGWDTLNFITEEIKNPERNLPLSIAISMPIVTIIYILTNVAYY 261

  Fly   289 SVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAA 353
            :||..:.:|.|:||||||.|.:|||.||::|.:||.|.:|.||.:|.|:|||||||:|.||||..
Zfish   262 AVLDMNTLLQSEAVAVTFADYVLGYASWLIPLSVAISCYGGLNSSIIAASRLFFVGSREGHLPNV 326

  Fly   354 ISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPKTER 418
            :.:|:|...||:|:|:|.|.::|:.|.:.||:.||||.|:...||..:|:...:::|:|.|...|
Zfish   327 LCMIHVKRYTPIPALLFNGGMSLIYLCVRDVFQLINYFSFNYWLFIGLSIGSQIYLRFKAPDMPR 391

  Fly   419 PIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVYYLTIHKPVK----WLADTSQ 479
            |||::|..||:|.:..:|||:...........:|..:.|||.||||:.:|.|..    :|.....
Zfish   392 PIKLSLFFPIVYCLCSVFLVVVPLYSDTINSLVGIAVALSGAPVYYICVHLPPSSRPAFLGQMLD 456

  Fly   480 AINLWCSKFFIC 491
            ..:|...|...|
Zfish   457 TFSLQTQKLCYC 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	226/467 (48%)
si:dkeyp-120h9.1	NP_001093492.1	2A0308	12..466	CDD:273332	220/453 (49%)
si:dkeyp-120h9.1	NP_001093492.1	SLC5-6-like_sbd	16..>263	CDD:294310	134/246 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.860