Protein Alignment mnd and SLC7A10

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 217/628 - (34%)
• Similarity: 322/628 - (51%)
• Gaps: 165/628 - (26%)

  Fly    19 PPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWV 83
            |...|...|....|:  .|.|||:||||....||:|.|:|||||:||||||:.|||:|.:|.|||
Human    18 PSPSPVPGTVPGASE--RVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWV 80

  Fly    84 LSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIY 148
            |.|.::.:|:|||||||..||||||||||:...||.|..||.||.|:||:.||..|:.::||:.|
Human    81 LGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNY 145

  Fly   149 LLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLF 213
            :|:|.:|:|..|..|.::|:.|.:.:||.:|..:|:|.||:.|:|||.|::||.:|:|.|:..:|
Human   146 VLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIF 210

  Fly   214 DGNTEH---------WDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAI 269
            .|:.|.         |..|      ..|::||||..|.|::||||:||:||||:.|..:|||:||
Human   211 QGHFEELRPSNAFAFWMTP------SVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAI 269

  Fly   270 CISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMP--------FAVACS- 325
            .||:|:||.:|..||||||:.:||.|:|||:||||..| .:||  .|::|        :.:.|:
Human   270 FISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSG-PLLG--PWLLPRPLPRPYTWPLYCAH 331

  Fly   326 --TFGSLNGAIF----------------------------------------------------- 335
              ..|...|.:|
Human   332 PDLRGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGRD 396

  Fly   336 ----------------------------------------------------------------- 335
                                                                             
Human   397 TCRGRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPKL 461

  Fly   336 -----------ASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLIN 389
                       .::||.|.|||.||||:.:::|:|...||:|:|:.....|.:::.:.|.|.|||
Human   462 RPRMWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLIN 526

  Fly   390 YVSYVEALFTLISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTI 454
            |||::..|...:::.|||.:|:::|...|||||||.:|:.||:...||::||....|.|.|:|.|
Human   527 YVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVI 591

  Fly   455 IILSGIPVYYLTI---HKPVKWLADTSQAINLWCSKF-FICMP 493
            |||:|:|:::|.:   .|| |.:...::::..|..:. |:..|
Human   592 IILTGVPIFFLGVFWRSKP-KCVHRLTESMTHWGQELCFVVYP 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	216/625 (35%)
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	217/628 (35%)