DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and slc7a10b

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	XP_687825.2	Gene:	slc7a10b / 559395	ZFINID:	ZDB-GENE-121105-2	Length:	517	Species:	Danio rerio

Alignment Length:	477	Identity:	228/477 - (47%)
Similarity:	322/477 - (67%)	Gaps:	19/477 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGA 93
            |||.. ..|.|||:||||....||:|.|:|||||:||||||:.|||:|.:|:||:|.|.::.:|:
Zfish    24 DSGIP-ERVTLKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALVVWMLGGGVAALGS 87

  Fly    94 LCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCD 158
            |||||||..||||||||:|:...||.|..||.||.|:||:.||..|:.||||:.|:|:|.:|.|.
Zfish    88 LCYAELGVTIPKSGGDYSYVTEIFGGLVGFLLLWSAVLIMYPTTLAVIALTFSSYVLQPVFPHCV 152

  Fly   159 APIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEHW--D 221
            .|..|.::|:|..|..||.:|||:|:..||:.|.||..|::||.:|:..|:..:..||.|..  .
Zfish   153 PPYIATRMLSAICILFLTWVNCYSVRLATRIQDAFTVGKLLALGLIITVGLVQICGGNYESLTPQ 217

  Fly   222 NPFS-GGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNI 285
            ..|: ......|.|||||....|::||||:||:||||:.||.||||:||.||:|:||.:|.:|||
Zfish   218 TAFTFNKAPSIGQIALAFLHASFAFSGWNFLNYVTEEVVDPRRNLPRAIYISIPLVTCVYTLTNI 282

  Fly   286 AYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHL 350
            ||||.:||:|:|||:|||||||:|:||..|.:||.:||.||||.:||.:|.||||.|.|||.|||
Zfish   283 AYFSSMSPEELLSSNAVAVTFGEKLLGMFSTLMPISVALSTFGGINGYLFTSSRLCFSGAREGHL 347

  Fly   351 PAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPK 415
            |:.:::|:....||:|:|:.....|:::|.|.:.:.||||||::..|...::::|||:.|:|:|.
Zfish   348 PSLLAMIHFKHCTPIPALLVCCTATIVILCIGETHNLINYVSFINYLSYGVTIAGLLYYRWKKPN 412

  Fly   416 TERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVYYLTIH---KP------V 471
            ..|||||:|.:|:.||:....|:.||....|.|.|:|.:|:|:|:|||:|.::   ||      .
Zfish   413 LYRPIKVSLLVPVCYLLFWALLLAFSLHSEPLVCGVGLVIMLTGVPVYFLGVYWKDKPRCIYDFT 477

  Fly   472 KWLADTSQAINLWCSKFFICMP 493
            :|.....|.:      ||:..|
Zfish   478 EWATYLGQRV------FFVVFP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	228/477 (48%)
slc7a10b	XP_687825.2	2A0308	29..494	CDD:273332	225/471 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	448	1.000	Inparanoid score	I1598
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.700