DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and Slc7a6

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	XP_006531198.1	Gene:	Slc7a6 / 330836	MGIID:	2142598	Length:	532	Species:	Mus musculus

Alignment Length:	460	Identity:	245/460 - (53%)
Similarity:	332/460 - (72%)	Gaps:	10/460 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VPPAEPNNSTADSGSQGSG----VKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQS 78
            :|.|..:....|:||...|    ::|||:|.||:||:::||.::|||||||||||||::.|.|.|
Mouse    33 LPKANQHTVKEDAGSPSQGSPETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLS 97

  Fly    79 LIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITAL 143
            ||||.:.|:.|:|||||||||||.|.|||..||||..|||...||:.|||:|||:.||..||.|:
Mouse    98 LIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAI 162

  Fly   144 TFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAG 208
            |||.|::||.:|:||.|..|.:|||||.:|:||.:||..|||.|||.|.||..||:||:.|:..|
Mouse   163 TFANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMG 227

  Fly   209 VWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISM 273
            :..|..|:|||:.:.|.|...:.|.::||.||.|||||||:.|||||||:|:|.||||.||.|||
Mouse   228 LVKLCQGHTEHFQDAFKGSSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISM 292

  Fly   274 PVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASS 338
            |:||:||::||:||::||:..::..||||||||.|:..|..||.:|.|||.|.||.||.:|||||
Mouse   293 PIVTLIYILTNVAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASS 357

  Fly   339 RLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISV 403
            ||||||:|.||||..:|:|::...||||:|:|...:||:.|.::||::||||.|:....|..:||
Mouse   358 RLFFVGSREGHLPNLLSMIHIERFTPVPALLFNCTMTLIYLVVKDVFLLINYFSFSYWFFVGLSV 422

  Fly   404 SGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLV---IFSCTQTPYVVGIGTIIILSGIPVYYL 465
            .|.|::|:|:|...||:|::|..||::.:..||||   :||.|... ::|||  |.|||:|||:|
Mouse   423 VGQLYLRWKEPDWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDTINS-LIGIG--IALSGVPVYFL 484

  Fly   466 TIHKP 470
            .::.|
Mouse   485 GVYLP 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	243/456 (53%)
Slc7a6	XP_006531198.1	2A0308	34..518	CDD:273332	245/459 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847687
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	LDO	PTHR11785
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.790