DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mnd and Slc7a15

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001033749.1	Gene:	Slc7a15 / 328059	MGIID:	3045351	Length:	488	Species:	Mus musculus

Alignment Length:	448	Identity:	194/448 - (43%)
Similarity:	289/448 - (64%)	Gaps:	12/448 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 DSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGA 93
            :.||..:|:.||::|||...|::..|.::|||||:||:|||.:.||.|.|||||...|:|:|:||
Mouse    17 EQGSGTAGLMLKREIGLWSAVSMTAGCMIGSGIFMSPQGVLVYIGSPGASLIVWATCGLLAMLGA 81

  Fly    94 LCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCD 158
            |||||||:::|:||||||||...||.|||||.::|.:|:..|.|....:|:||.|:|.||:|.|.
Mouse    82 LCYAELGSLVPESGGDYAYILRTFGSLPAFLVIYVYVLVGRPAGITAVSLSFAEYVLAPFYPGCS 146

  Fly   159 A-PIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDG--NTEHW 220
            : |...|:::|::.|.:|.|||.::.:..|.:.::.|..||.:|||||..|...|..|  :||..
Mouse   147 SLPQVIVKIVASSCILLLLLINFWSSRMSTVLMNVCTTAKVFSLLVIVVGGAVVLMQGHASTESL 211

  Fly   221 DNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNI 285
            ...|....|..|.|.:|||.||:|:.||:.:|.|.||||:|.:||..|:..::|:||::|::.||
Mouse   212 LFAFHNTTQQAGRIGMAFYQGLWSFDGWSNINTVIEELKNPKQNLLWAVMTAVPLVTILYVLVNI 276

  Fly   286 AYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHL 350
            :|..|:||.|||||||:||.:||::||..:|::|.|||.||||::||..|:.||:.:..||.||:
Mouse   277 SYLLVMSPSEILSSDAIAVIWGDRVLGSWAWLVPLAVALSTFGTVNGGFFSGSRVCYAAAREGHM 341

  Fly   351 PAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPK 415
            |..:|:|:||.|||.|:.||...:.|||:...:....:|.:|::..|....:.:.||::|.|...
Mouse   342 PQLMSMIHVNRLTPAPAQIFTTAVALLLVIPGNFSTFVNLLSFLSWLTYGTTFACLLYLRIKTKN 406

  Fly   416 TERPIKVNLALPIIYLIVCLFLVIFSCTQTP-----YVVGIGTIIILSGIPVYYLTIH 468
            .....||...:|.|.|:|.|:||:......|     |:.    :.:|||.|||:|..|
Mouse   407 LPHTYKVPTFIPAIMLLVSLYLVLAPIIDHPQIEFLYIF----LFVLSGFPVYFLLFH 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	194/448 (43%)
Slc7a15	NP_001033749.1	2A0308	5..481	CDD:273332	194/448 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.760