DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and Slc7a9

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001185944.1	Gene:	Slc7a9 / 30962	MGIID:	1353656	Length:	487	Species:	Mus musculus

Alignment Length:	448	Identity:	201/448 - (44%)
Similarity:	299/448 - (66%)	Gaps:	9/448 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELGTMI 103
            |:|::|||.|:.||||.|:|||||:|||.||..:.|:|..||:|...|:|:.:||||:|||||||
Mouse    26 LQKEVGLLSGICIIVGTIIGSGIFISPKSVLANTESVGPCLIIWAACGILATLGALCFAELGTMI 90

  Fly   104 PKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQLLA 168
            .||||:|.|:..||||:||:|:.|.:|:::.|:..||..|:|:.|:...|:..|..|...|:|||
Mouse    91 TKSGGEYPYLMEAFGPIPAYLFSWTSLIVMKPSSFAIICLSFSEYVCAAFYSGCKPPAVVVKLLA 155

  Fly   169 AAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEHWDNPFSGGLQDPGY 233
            ||.|..:|.:|..:|:..:.|.::||..|:|.:.:|:.:|:.:|..||.:::.|.|.|.....|.
Mouse   156 AAAILFITTVNALSVRLGSYVQNVFTAAKMVIVAIIIISGLVFLAQGNVKNFQNSFEGTQTSVGA 220

  Fly   234 IALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILS 298
            |:||||:||::|.|||.||::||||::||||||.||.|.:|:|||.|::.|||||:|::|.|:|.
Mouse   221 ISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPMAIVIGIPLVTVCYILMNIAYFTVMTPTELLQ 285

  Fly   299 SDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLT 363
            |.||||||||::|...||::|..||.||.|:.||..|.:.||.:|..|.||:...:|.|:|..||
Mouse   286 SQAVAVTFGDRVLYPASWVVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVKRLT 350

  Fly   364 PVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPKTERPIKVNLALPI 428
            |.|:|||.|::.::.:...|:..|:||.|:...||..:::.||:.||:.:...||||||.|.:||
Mouse   351 PAPALIFYGIIAIIYIIPGDINSLVNYFSFAAWLFYGMTILGLVVMRFTRKDLERPIKVPLFIPI 415

  Fly   429 IYLIVCLFLVIFSCTQTP-----YVVGIGTIIILSGIPVYYLTIHKPVKWLADTSQAI 481
            |.::|.|||::......|     |.|    :.||||:..|:|.::....|....|:.:
Mouse   416 IVILVSLFLILAPIISEPAWEYLYCV----LFILSGLIFYFLFVYYKFGWAQRISRPV 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	201/448 (45%)
Slc7a9	NP_001185944.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
Slc7a9	NP_001185944.1	2A0308	26..484	CDD:273332	201/448 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847684
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.690