Protein Alignment mnd and Slc7a12

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001011948.1
• Gene: Slc7a12 / 294881
• RGDID: 1309208
• Length: 472
• Species: Rattus norvegicus
• Alignment Length: 436
• Identity: 131/436 - (30%)
• Similarity: 231/436 - (52%)
• Gaps: 11/436 - (2%)

  Fly    37 VKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKF-SGSIGQSLIVWVLSGVLSMVGALCYAELG 100
            ::|.:.:|.......:....:|:|||||||||||: |.:|...|.:|...|:|||:.|:|.||:.
  Rat     1 MQLLRGLGFFHVNMFLFSATIGTGIFVSPKGVLKYCSLNIPIFLSIWAGCGLLSMMNAVCLAEIA 65

  Fly   101 TMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQ 165
            ...|.||..|.::..|.|...|||.:|:.:.... .|.:...|..|..|::.|:..|.||....:
  Rat    66 ATYPVSGASYYFLKRALGSSVAFLSIWIKIFACT-LGISAQCLLIASSLIQCFYSECQAPELPKK 129

  Fly   166 LLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDG---NTEHWDNPFSGG 227
            .||.|::....:::...:|.|.....|.:..|:..|.:|...|:..|..|   |...::......
  Rat   130 CLALAILWSFGILSARGIKPVAWFNTISSLMKLSVLCLISLTGIVLLVIGKKENVSRFEKALEAE 194

  Fly   228 LQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLS 292
            |.:...||.|.....::|.|.::|..:..|:|.|...:||:|...:.||||:|::||:::.:||:
  Rat   195 LPNVSQIAEAILQVYYAYLGSSFLIVIAGEIKRPAETIPKSIIYGLSVVTVLYLLTNVSFLAVLT 259

  Fly   293 PDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLI 357
            .:||:|||:||||:.:::...|.||:...::...|||::..|.::||:|:..::.|..|...|::
  Rat   260 SEEIISSDSVAVTWMNRVFPSMQWIISLLISAFLFGSVSCGIVSASRIFYATSQEGQFPFIYSML 324

  Fly   358 NVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPKTERPIKV 422
            | :..:||.:.:...:|:.:.:...::..||.||........|:::.|||.:||:.|...||.||
  Rat   325 N-DLHSPVVADLQAVILSSVGIISSNMIYLIKYVGLGTWCLNLLNMIGLLKLRYQNPDLPRPYKV 388

  Fly   423 NLALPIIY--LIVCLFLVIFSCTQTPYVVGIGTIIIL-SGIPVYYL 465
            .  ||.::  :...|||::....|:|....:..::.| .|:..|:|
  Rat   389 R--LPFVFGSIASSLFLILTPVIQSPSTEHVYQVVFLFCGLLCYWL 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	131/436 (30%)
Slc7a12	NP_001011948.1	2A0308	21..423	CDD:273332	125/405 (31%)