Protein Alignment mnd and Slc7a3

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_058913.2
• Gene: Slc7a3 / 29485
• RGDID: 68342
• Length: 619
• Species: Rattus norvegicus
• Alignment Length: 604
• Identity: 131/604 - (21%)
• Similarity: 226/604 - (37%)
• Gaps: 172/604 - (28%)

  Fly    10 LIPRQVFEVPPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGS 74
            |:.|:|.|:...|              .:|.:.:..||.||:.||..:|:|::|....|.|  ..
  Rat    13 LVRRRVLELGMGE--------------TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--EK 61

  Fly    75 IGQSLIVWVLSGVLSMV-GALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILV---- 134
            .|.|:::..|...||.| ..|||||.|..:|.||..|.|.....|.|.||...|..:|..|
  Rat    62 AGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTA 126

  Fly   135 ------------PTGNAIT-ALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWV 186
                        ..||.|: .|...|.|..|     ....|.....|.|::.:||.:........
  Rat   127 SVARAWSSAFDNLIGNHISQTLKGTILLNMP-----HVLAEYPDFFALALVLLLTGLLVLGANES 186

  Fly   187 TRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEHW--------------------DNPFSGGLQDP 231
            ..||.:|||..::.|..::.:|   ...|...:|                    |:..|||....
  Rat   187 ALVTKVFTGMNLLVLGFVIISG---FIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPF 248

  Fly   232 GY------IALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYM-----ITNI 285
            |.      .|..||    ::.|::.:....||.::|.|::|..|.||:.:..:.|.     :|.:
  Rat   249 GLEGILRGAATCFY----AFVGFDCIATTGEEAQNPQRSIPMGIVISLSICFLAYFGVSSALTLM 309

  Fly   286 AYFSVLSPDEILSSDAVAVTFGDKMLGYMSW-----IMPFAVACSTFGSLNGAIFASSRLFFVGA 345
            ..:..|.|:..|          .:...|:.|     ::.....|:...||.|::|...|:.:..|
  Rat   310 MPYYKLQPESPL----------PEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVIYAMA 364

  Fly   346 RNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEAL-FTLISVSGLLWM 409
            .:|.|...::.::....||:.:.:..||:...:.|:.::..|::.:|....| ::|:|:..|: :
  Rat   365 EDGLLFRVLARVHNGTHTPIVATVVSGVIAAFMAFLFELTDLVDLMSIGTLLAYSLVSICVLI-L 428

  Fly   410 RYKQPKTE------------------------------RPIKVNLALPIIYL----------IVC 434
            || ||..|                              ..|...|:..|:|:          ::|
  Rat   429 RY-QPDQEMKNGEEEVELQEEETLEAEKLTVQALFCPVNSIPTLLSGRIVYVCSSLLAVLLTVLC 492

  Fly   435 LFLVIFSCTQTP-----------YVVGIGTIIILSG---------------IPV--------YYL 465
            |.|..::   ||           .|:.:|.|:.:||               :||        .::
  Rat   493 LVLTWWT---TPLHSGDPVWVTVVVLILGLILGISGVIWRQPQNRTPLHFKVPVVPLLPLVSIFV 554

  Fly   466 TIHKPVKWLADTSQAINLW 484
            .::..::..|||.....:|
  Rat   555 NVYLMMQMTADTWARFGVW 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	127/592 (21%)
Slc7a3	NP_058913.2	2A0303	4..591	CDD:273330	131/604 (22%)