Protein Alignment mnd and Slc7a11

DIOPT Version :9

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_036120.1
• Gene: Slc7a11 / 26570
• MGIID: 1347355
• Length: 502
• Species: Mus musculus
• Alignment Length: 489
• Identity: 215/489 - (43%)
• Similarity: 314/489 - (64%)
• Gaps: 14/489 - (2%)

  Fly    11 IPRQVFEVPPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSI 75
            :|....:.||.:..            |.|||:|.||.||:||:|.::|||||:||||:|:.:||:
Mouse    24 LPSMGDQEPPGQEK------------VVLKKKITLLRGVSIIIGTVIGSGIFISPKGILQNTGSV 76

  Fly    76 GQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAI 140
            |.||:.|...||||:.|||.||||||.|.||||.|.||...||||.||:.:||.||::.|...|:
Mouse    77 GMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVFGPLLAFVRVWVELLVIRPGATAV 141

  Fly   141 TALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIV 205
            .:|.|..|:|:||:..|:.|..|::|:.|..|.|:.::|..:|.|..|:....|..|:.|:|:|:
Mouse   142 ISLAFGRYILEPFFIQCEIPELAIKLVTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIII 206

  Fly   206 GAGVWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAIC 270
            ..||..|..|.|.|:.:.|||.......:.||||.|:::|:||.||||:|||:.:|.:.:|.|||
Mouse   207 VPGVIQLIKGQTHHFKDAFSGRDTSLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAIC 271

  Fly   271 ISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIF 335
            |||.::||.|::||:|||:.:|.:|:|.|.||||||.:::||..|..:|..||.|.|||:||.:|
Mouse   272 ISMAIITVGYVLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVALSCFGSMNGGVF 336

  Fly   336 ASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTL 400
            |.||||:|.:|.||||..:|:|:|:..||:|::|.|..||:::||..|:|.|:|::|:...||..
Mouse   337 AVSRLFYVASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMVMLFSGDLYSLLNFLSFARWLFMG 401

  Fly   401 ISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVYYL 465
            ::|:||:::|||:|...||.||.|.:|.::...|||:|:.|....|:..|:|.:|.|:|:|.|||
Mouse   402 LAVAGLIYLRYKRPDMHRPFKVPLFIPALFSFTCLFMVVLSLYSDPFSTGVGFLITLTGVPAYYL 466

  Fly   466 TI--HKPVKWLADTSQAINLWCSKFFICMPNQEK 497
            .|  .|..||....|..|..........:|...|
Mouse   467 FIVWDKKPKWFRRLSDRITRTLQIILEVVPEDSK 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	211/475 (44%)
Slc7a11	NP_036120.1	2A0308	1..498	CDD:273332	214/485 (44%)
		SLC5-6-like_sbd	42..>291	CDD:294310	120/248 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847644
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750