DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mnd and Slc7a1

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_037243.2	Gene:	Slc7a1 / 25648	RGDID:	3716	Length:	624	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	107/429 - (24%)
Similarity:	195/429 - (45%)	Gaps:	70/429 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 KLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIV-WVLSGVLSMVGALCYAELGT 101
            :|.:.:...|.||:.||..:|:|::|....|.:  .:.|.:::: ::::.:.|::..|||.|.|.
  Rat    27 RLSRCLNTYDLVALGVGSTLGAGVYVLAGAVAR--ENAGPAIVISFLIAALASVLAGLCYGEFGA 89

  Fly   102 MIPKSGGDYAYIGTAFGPLPAFLYLW-VALLILVPTGNAITA--LTFAIYLLKPFWP------SC 157
            .:||:|..|.|.....|.|.||:..| :.|..::.|.:...|  .||...:.||...      :.
  Rat    90 RVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMAL 154

  Fly   158 DAP---IEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEH 219
            :||   .:...:.|..:|.:||.:....||....|..|||...|:.|..|:.:|   ...|:.|:
  Rat   155 NAPGVLAQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLCFIMVSG---FVKGSIEN 216

  Fly   220 W------DNPFSGG------LQDPGYIALAFYSGL--------FSYSGWNYLNFVTEELKDPYRN 264
            |      .:|..|.      ..:.|::...| ||:        :::.|::.:....||:|:|.:.
  Rat   217 WQLTENKSSPLCGNNDTNVKYGEGGFMPFGF-SGVLSGAATCFYAFVGFDCIATTGEEVKNPQKA 280

  Fly   265 LPKAICISMPVVTVIYMITNIAYFSV------LSPDEILSSDAVAVTFGDKMLG---YMSW-IMP 319
            :|..|..|:       :|..||||.|      :.|...|.:|:       .:.|   |..| ...
  Rat   281 IPVGIVASL-------LICFIAYFGVSAALTLMMPYFCLDTDS-------PLPGAFKYRGWEEAK 331

  Fly   320 FAVA----CSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLF 380
            :|||    |:...||.|::|...|:.:..|.:|.|...::.||....||:.:.:..|.:..::.|
  Rat   332 YAVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFKFLAKINDRTKTPIIATVTSGAIAAVMAF 396

  Fly   381 IEDVYVLINYVSYVEALFTLISVSGLLWMRYKQPKTERP 419
            :.::..|::.:|....|...:..:.:|.:|| ||  |:|
  Rat   397 LFELKDLVDLMSIGTLLAYSLVAACVLVLRY-QP--EQP 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	107/429 (25%)
Slc7a1	NP_037243.2	2A0303	4..605	CDD:273330	107/429 (25%)
Slc7a1	NP_037243.2	AA_permease_C	553..603	CDD:290617
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940