DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mnd and thi9

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_593353.1	Gene:	thi9 / 2543578	PomBaseID:	SPAC9.10	Length:	591	Species:	Schizosaccharomyces pombe

Alignment Length:	510	Identity:	111/510 - (21%)
Similarity:	186/510 - (36%)	Gaps:	137/510 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 LKFSG--SIGQSLIVW---VLSGVLSMVGALCYAELGTMIPKSGGDYAY----IGTAFGPLPAFL 124
            |.||.  |.|.....|   :::|..|:|.|.|.||:.:.:|.:|..|.:    .|..||...:||
pombe    98 LTFSWGISFGGPAAYWSAMLVTGFCSIVTAACLAEICSALPAAGSIYLWAAESAGPRFGRFVSFL 162

  Fly   125 YLWVALLILVPTGNAITALT--FAIYLLKPF---WPSCDAPIE--AVQLLAAAMICVLT-LIN-- 179
            ..|.:.........:||..|  |....:..|   ||:.|:.::  |||.:.|.::.|.| |:|
pombe   163 VAWWSTTAWTTFVASITQSTANFIFAEVSTFNNPWPTNDSDVKFRAVQWIVAEVLLVFTILLNQV 227

  Fly   180 --------------------CYNVKWVTRVTD-----------IFT-----------------GT 196
                                ..|:.||...|.           :||                 |.
pombe   228 PPRYYKWIFKASMLLMFIDYVMNIIWVPVATSKKPDGFRSAKWVFTETIYDQAGYIKEVDDANGN 292

  Fly   197 KVVALLVIVGAGVWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDP 261
            .:.:|..||..|..|                       .|::::......|::....:.||.||.
pombe   293 PIASLSKIVPKGWQW-----------------------CLSYFATAGVIVGYDASGHIAEETKDA 334

  Fly   262 YRNLPKAICISMPVVTVIYMITNIAYFSVLSPD-----EILSSD---AVAVTFGDKMLGYMSW-I 317
            .....:.|..|.....::.....|.|. ...||     .||.:|   ...|.|...:||.... :
pombe   335 SIKAARGIFYSTVTSFIVAFSLAILYL-FCCPDLDTFTAILYNDNSPQPFVNFYSYLLGRGGHVV 398

  Fly   318 MPFAVACSTFGSLNG--AIFASSRLFFVGARNGHLPAA--ISLIN-----VNCLTPVPSLIFLGV 373
            |...:....|  |||  ::.|.|||.|..:|:|.||.:  ||.::     .|.:|    :|::..
pombe   399 MNVVIILEIF--LNGVVSVLACSRLVFAVSRDGVLPFSNWISQVSKTGQPKNAIT----VIYIVS 457

  Fly   374 LTLLLLFIEDVYVLINYVSYVE----ALFTLISVSGLLWMRYKQPKTERPI----KVNLALPIIY 430
            ..||...:.......:.||...    |.:.:::...|...|.|.||....:    |..|.:.::|
pombe   458 ALLLCTILPSAVAFTSLVSAAGAPSFAAYAVLAFCRLFITRDKFPKGRWSLGWLSKPCLVITLVY 522

  Fly   431 LIVCLFLVIFSCTQTPYVVGIG------TIIILSGIPVYYL--TIHKP-VKWLAD 476
            .:..|.:.:     :||...:.      .::|:.|:.::.:  ||..| .:|:|:
pombe   523 NLFALVVNV-----SPYTYPVTGPSFNYAVVIMGGVSIFAIICTIVIPKSRWVAN 572

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	111/510 (22%)
thi9	NP_593353.1	2A0304	64..559	CDD:273331	106/495 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I1915
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.050