Protein Alignment mnd and nrg1

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_596849.1
• Gene: nrg1 / 2541403
• PomBaseID: SPBPB2B2.01
• Length: 585
• Species: Schizosaccharomyces pombe
• Alignment Length: 553
• Identity: 119/553 - (21%)
• Similarity: 206/553 - (37%)
• Gaps: 142/553 - (25%)

  Fly    14 QVFEVPPAEPN------------NSTADSGSQGSGVKLK----KQIGLLDGVAIIVGVIVGSGIF 62
            :|..||..|.|            .:..||..||...:||    :.||        :|..:|:|::
pombe    46 EVETVPAKEENVFRRFINGFKIEKNQQDSAGQGLKRRLKSRHIQMIG--------IGGAIGTGVW 102

  Fly    63 VSPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYA----YIGTAFGPLPAF 123
            |.....| :.|.....||.:.:.|.:.........||....|..|....    :|..::|...::
pombe   103 VGSSKSL-YRGGAASVLIDYCIVGTMVFCTVYALGELAVAFPTRGSFVTHATRFIDESWGFALSW 166

  Fly   124 LYLWVALLILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTR 188
            .|:: :.::.:|     ..||....::| :|.:.::.|     .....|..|..||.:.||....
pombe   167 NYVF-SFIVTIP-----LELTTGTMMIK-YWTNLNSGI-----WVTVFIVFLFFINIFGVKGYGE 219

  Fly   189 VTDIFTGTKVVAL--LVIVG-----AGVWWLFDGNTEH---------WDNPFSGGLQDPGYIALA 237
            :..|.:..||||:  .:|:|     .||      .|:|         .:|.|....:  |:.|:
pombe   220 MEFIMSTIKVVAMCGFIILGIIIDCGGV------PTDHRGYMGTHIFRENAFRHKFK--GFCAV- 275

  Fly   238 FYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMIT-NIAYFSVLSPDEILSS-- 299
            |.|..||:||..|:.....|.::|.:..|.|:..::..:.:.|::: .|....:...|..|:|
pombe   276 FTSAAFSFSGTEYVGVAAAETENPAKAFPVAVRQTLFRIAIFYILSLFIVSLLISGADPRLTSYH 340

  Fly   300 --DA--VAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVN 360
              ||  ..:...|..:..:..|:...:..|...|.|..::|.||.......||..|...:|::..
pombe   341 GVDASPFVLAIKDANIKALPSILNAIILISVISSANAQLYAGSRAIHSLGCNGFAPKCFTLVDRE 405

  Fly   361 CLTPVPSLIFLG--VLTLLLLFIEDVYVLINYV----SYVEALFTLISVSGL----LW------- 408
                       |  ::.||:||:   ::.:.|:    .|......::|:|||    .|
pombe   406 -----------GRPLVALLILFL---FMFLGYLVETGQYDTVFDWMLSISGLGTLFCWGSICLAH 456

  Fly   409 MRYK--QPKTERPIK-VNLALPI-------IYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVY 463
            :||:  .....|.:| |....|.       .:::|||.|.                      ..:
pombe   457 IRYRAAMKHQNRSLKEVGFVSPFNVYASYYAFILVCLVLA----------------------AEF 499

  Fly   464 YLTIHKPVKWLADTSQAINLWCSK-----FFIC 491
            |::|. ||....|.|.....:.|.     ||||
pombe   500 YVSIF-PVGGKPDASAFFENYLSAPVILVFFIC 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	116/545 (21%)
nrg1	NP_596849.1	AA_permease_2	80..549	CDD:459263	110/519 (21%)