Protein Alignment mnd and aat1

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_595053.1
• Gene: aat1 / 2541042
• PomBaseID: SPBC359.03C
• Length: 579
• Species: Schizosaccharomyces pombe
• Alignment Length: 502
• Identity: 97/502 - (19%)
• Similarity: 176/502 - (35%)
• Gaps: 111/502 - (22%)

  Fly    36 GVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELG 100
            |..||:.:.......:.:|..:|||::|.....|. .|.....:|.::|.|::.........|:.
pombe    70 GPALKRGLSTRHMQLMSIGGAIGSGLYVGSGSALA-DGGPASVIINYILIGIMMFFVIYALGEMA 133

  Fly   101 TMIPKSGGDYAYIGTAFGPLPAFLYLW---VALLILVPTGNAITALTFAIYLLKPFWPSCDAPIE 162
            ...|.:|....|......|...|...|   ....:..|......|:||.      ||...:..:
pombe   134 VAYPVAGSFNTYATRFIDPAWGFAVSWNYFFNYFVTFPFELTTCAITFT------FWTDVNCAV- 191

  Fly   163 AVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVA------LLVIVGAGVWWLFDGNTEH-- 219
                ..:..:.|:..||.:.|:....|..:....||||      |.:|:..|     ...|:|
pombe   192 ----WISIFLVVVIGINLFGVRVFGEVEFVLALIKVVATVGFIILAIIINCG-----GVPTDHRG 247

  Fly   220 -------WDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVT 277
                   ...||..|.:  |:.:: :.:..||:||...:.....|:.||.:.||.|:......|.
pombe   248 YIGGSIIKQKPFRHGFK--GFCSV-YTTAAFSFSGTEIVGLAAAEVGDPRKTLPGAVKQVFWRVA 309

  Fly   278 VIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMS-WIMPFAVAC---------STFGSL-- 330
            :.|:::.|....::|||:            .|::|..| .:.||.:|.         |.|.::
pombe   310 IFYIVSLILIGLLISPDD------------PKLMGNGSASVSPFVLAIQEANIKGLPSVFNAVII 362

  Fly   331 -------NGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTL-LLLFIEDVYVL 387
                   |.:.:.:.|... |..|  |..|.:..........|.:..:.||:. ...:|.:....
pombe   363 ISVISVTNSSTYTAGRTLH-GMAN--LKQAPAFFKYTDRLGRPLIAMIVVLSFGFFAYINEANNN 424

  Fly   388 INYVSYVEALFT-LISVSGL-------------LWMRYKQPKTERPIK--------------VNL 424
            .|.:|  :.:|. |:::|||             :..|....|....:|              :.|
pombe   425 GNDIS--DTVFDWLLAISGLSNFFTWGSICLSHIMFRLAFKKQGHSLKELGFVSPMGIWGSVIGL 487

  Fly   425 ALPIIYLIVCLFLVIFSCTQTP--------YVVGIGTIIILSGIPVY 463
            ...|:.|:...::.:|....:|        |:....|::...|..:|
pombe   488 GFNILCLMAEFYVSLFPIGGSPNANDFFQGYLAACITLVFFIGYKIY 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	97/502 (19%)
aat1	NP_595053.1	AA_permease_2	74..548	CDD:459263	95/498 (19%)