Protein Alignment mnd and SLC7A8

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_036376.2
• Gene: SLC7A8 / 23428
• HGNCID: 11066
• Length: 535
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 244/492 - (49%)
• Similarity: 348/492 - (70%)
• Gaps: 20/492 - (4%)

  Fly    19 PPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIVWV 83
            |....::::.::||.|.||.|||:|||:....||||.|:||||||||||||:.:||:|.:||||:
Human    16 PGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWI 80

  Fly    84 LSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIY 148
            ::|.:::||||||||||..||||||||:|:...||.|..||.||:|:|::.||..|:.||||:.|
Human    81 VTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNY 145

  Fly   149 LLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGV---- 209
            :|:|.:|:|..|...::||||..:.:||.:||.:|:|.|||.||||..|::||.:|:..|:
Human   146 VLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQIC 210

  Fly   210 ----WWLFDGNT-EHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAI 269
                :||...|. |::..|      |.|.:||||..|.|:|.|||:||:|||||.|||:|||:||
Human   211 KGEYFWLEPKNAFENFQEP------DIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAI 269

  Fly   270 CISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNGAI 334
            .||:|:||.:|:..|:||.:.:||.|:|:|:|||||||:|:||.|:||||.:||.||||.:||::
Human   270 FISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSL 334

  Fly   335 FASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEALFT 399
            |.||||||.|||.||||:.:::|:|...||:|:|:|..:.|||:|...|:|.|||||.::..||.
Human   335 FTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFY 399

  Fly   400 LISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGTIIILSGIPVYY 464
            .::|:|.:.:|:|:|...||||:||..|||||:...||::||....|.|.|||..|:|:|:|||:
Human   400 GVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYF 464

  Fly   465 LTI---HKPVKWLADTSQAINLWCSKFFICM-PNQEK 497
            |.:   ||| |..:|..:.:.|...|..:.: |..|:
Human   465 LGVYWQHKP-KCFSDFIELLTLVSQKMCVVVYPEVER 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	242/486 (50%)
SLC7A8	NP_036376.2	2A0308	1..497	CDD:273332	242/487 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		2/13 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	502..535