DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mnd and Slc7a7

DIOPT Version :9

Sequence 1:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	XP_030103562.1	Gene:	Slc7a7 / 20540	MGIID:	1337120	Length:	596	Species:	Mus musculus

Alignment Length:	466	Identity:	248/466 - (53%)
Similarity:	325/466 - (69%)	Gaps:	23/466 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 NST---------ADSGSQ-GSG-------VKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFS 72
            |||         ||.||. |.|       |||||:|.||:||.:|||.::||||||||||||.:|
Mouse    89 NSTKYEVAAQHEADDGSALGDGASPVAEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYS 153

  Fly    73 GSIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTG 137
            .|.|.||::|.:.|:.|:.||||||||||.|.|||..||||..|||...||:.||.:|||:.||.
Mouse   154 ASFGLSLVIWAVGGIFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTS 218

  Fly   138 NAITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALL 202
            .|:.|:|||.|:::|.:|||.||..|.:|||||.||:||.|||..|||.|.|.||||..||:||:
Mouse   219 QAVIAITFANYMVQPLFPSCGAPYAAGRLLAAACICLLTFINCAYVKWGTLVQDIFTYAKVLALI 283

  Fly   203 VIVGAGVWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPK 267
            .::.||:..|..|.|.:::|.|.|.....|.||||.||.|||||||:.||:||||:::|.||||.
Mouse   284 AVIIAGIVRLGQGATANFENSFEGSSFAMGDIALALYSALFSYSGWDTLNYVTEEIRNPERNLPL 348

  Fly   268 AICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVACSTFGSLNG 332
            :|.||||:||:||::||:||:|||...|||:||||||||.|::.|..:||:|.|||.|.||.||.
Mouse   349 SIGISMPIVTIIYLLTNVAYYSVLDIKEILASDAVAVTFADQIFGVFNWIIPVAVAFSCFGGLNA 413

  Fly   333 AIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEAL 397
            :|.|:|||.|||:|.||||.||.:::|...||||||:|.|||:|:.|.:||::.||||.|:....
Mouse   414 SIVAASRLLFVGSREGHLPDAICMVHVERFTPVPSLLFNGVLSLVYLCVEDIFQLINYYSFSYWF 478

  Fly   398 FTLISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLV---IFSCTQTPYVVGIGTIIILSG 459
            |..:|:.|.|::|:|.|...||:|::|..|||:.:..:|||   ::|.|... ::|||  |.|||
Mouse   479 FVGLSIVGQLYLRWKDPDRPRPLKLSLFFPIIFCLCTIFLVAVPLYSDTINS-LIGIG--IALSG 540

  Fly   460 IPVYYLTIHKP 470
            :|.|:..|..|
Mouse   541 LPFYFFIIRVP 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	248/466 (53%)
Slc7a7	XP_030103562.1	2A0308	107..580	CDD:273332	241/448 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847621
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H88701
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.790