Protein Alignment mnd and C50D2.2

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_493662.1
• Gene: C50D2.2 / 183650
• WormBaseID: WBGene00016806
• Length: 589
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 130/518 - (25%)
• Similarity: 221/518 - (42%)
• Gaps: 93/518 - (17%)

  Fly    39 LKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIV-WVLSGVLSMVGALCYAELGTM 102
            |::.:...|...:.||.::|:||:|....|::  .:.|.|:|: ::|:|..|::.||||||.|..
 Worm    25 LRRCLSTFDITLLGVGHMIGAGIYVLTGSVVR--NTAGPSIILSFLLAGFASLLSALCYAEFGAR 87

  Fly   103 IPKSGGDYAYIGTAFGPLPAFLYLWVALL-------------------ILVPTGNAITALTFA-- 146
            .||:|..|.|.....|.|.||:..|..:|                   :|   ||.|:..|.|
 Worm    88 FPKAGSAYTYTYVGVGELWAFVIGWNIILEHMLGAAAVARSWSGYLDSLL---GNVISNSTIART 149

  Fly   147 --IYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGV 209
              ::....|:.  |.|    .|||..:|.::........|..|......|...:..::::|..|:
 Worm   150 GHLHEASSFFG--DYP----DLLAFLLIVLVAFFVALGSKVSTNFNSFLTILNIGIVVIVVFYGI 208

  Fly   210 -------WWLFD--GNTEHWDNPFSGGLQDPGYIALAFYSG----LFSYSGWNYLNFVTEELKDP 261
                   |...|  ||:..:....||           .::|    .|:|.|::.|....||.|||
 Worm   209 TFADFSLWSGVDEKGNSRFFPYGVSG-----------MFAGAASCFFAYIGFDGLATAGEEAKDP 262

  Fly   262 YRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVAC-S 325
            .|::|.|...||.:||:.|::.: |..:::.|..::...|   .|.|......:....:||:. :
 Worm   263 ARSIPIATFSSMTIVTLSYVLMS-ASLTLMIPYNMVHPTA---AFSDAFTMRGAEFASYAVSVGA 323

  Fly   326 TFG---SLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVL 387
            .||   ||.|.:||..|..|..|.:|.|.::::.:|.....|..:|:..|.||.::..:.|:..|
 Worm   324 LFGMTTSLVGGMFALPRCVFSMADDGLLFSSLASVNPKTQVPTQALLIFGFLTAIIALLFDITTL 388

  Fly   388 INYVSYVEALFTLISVSGLLWMRYKQP-------KTERPIKVNLALPIIYLIVCLFLVIFSCTQT 445
            :.::|....|...|..:.::.:|| ||       :.:...|:..::|.     |.||.......:
 Worm   389 VEFLSIGTLLAYSIVSACVIVLRY-QPAYNVDEGQFDNGGKLRFSIPF-----CGFLDKLQPGHS 447

  Fly   446 PYVVGIGTII---ILSGI----PVYYLTIHKPVKWLADTSQAINLWCSKFFIC--MPNQEKFD 499
            .| .|:..:|   ..||:    ...|.|:...:..|.:.:..|   .|..|||  .||....|
 Worm   448 IY-YGMSVMIASMFFSGLGFSSGYLYGTVLCQIFLLVNIALII---LSFLFICAHYPNNTPLD 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	129/513 (25%)
C50D2.2	NP_493662.1	2A0303	6..559	CDD:273330	130/518 (25%)