Protein Alignment mnd and Slc7a3

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_031541.1
• Gene: Slc7a3 / 11989
• MGIID: 1100521
• Length: 618
• Species: Mus musculus
• Alignment Length: 608
• Identity: 128/608 - (21%)
• Similarity: 225/608 - (37%)
• Gaps: 181/608 - (29%)

  Fly    10 LIPRQVFEVPPAEPNNSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGS 74
            |:.|:|.|:...|              .:|.:.:..||.||:.||..:|:|::|....|.|  ..
Mouse    13 LVRRRVLELGMGE--------------TRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAK--DK 61

  Fly    75 IGQSLIVWVLSGVLSMV-GALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILV---- 134
            .|.|:::..|...||.| ..|||||.|..:|.||..|.|.....|.|.||...|..:|..|
Mouse    62 AGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTA 126

  Fly   135 ------------PTGNAITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVT 187
                        ..||.|:.......|||  .|...|  |.....|.|::.:||.:.........
Mouse   127 SVARAWSSAFDNLIGNHISRTLKGTILLK--MPHVLA--EYPDFFALALVLLLTGLLVLGASKSA 187

  Fly   188 RVTDIFTGTKVVALLVIVGAGVWWLFDGNTEHW--------------------DNPFSGGLQDPG 232
            .||.:|||..::.|..::.:|   ...|...:|                    |:..|||....|
Mouse   188 LVTKVFTGMNLLVLSFVIISG---FIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFG 249

  Fly   233 Y------IALAFYSGLFSYSGWNYLNFVTEELKDPYRNLPKAICISMPVVTVIYMITNIAYFSV- 290
            .      .|..||    ::.|::.:....||.::|.|::|..|.|||       .|..:|||.|
Mouse   250 LEGILRGAATCFY----AFVGFDCIATTGEEAQNPQRSIPMGIVISM-------FICFLAYFGVS 303

  Fly   291 -----------LSPDEILSSDAVAVTFGDKMLGYMSW-----IMPFAVACSTFGSLNGAIFASSR 339
                       |.|:..|          .:...|:.|     ::.....|:...||.|::|...|
Mouse   304 SALTLMMPYYKLHPESPL----------PEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPR 358

  Fly   340 LFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLINYVSYVEAL-FTLISV 403
            :.:..|.:|.|...::.::.....|:.:.:..||:...:.|:.::..|::.:|....| .:|:|:
Mouse   359 VMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSI 423

  Fly   404 SGLLWMRYKQPKTERPIKVNLALP----------------------------IIYL--------- 431
            ..|: :||:..:..:.::..:.|.                            ::|:
Mouse   424 CVLI-LRYQPDQEMKSVEEEMELQEETLEAEKLTVQALFCPVNSIPTLLSGRVVYVCSSLLAVLL 487

  Fly   432 -IVCLFLVIFSCTQTP-----------YVVGIGTIIILSGI---------PVY------------ 463
             ::||.|..::   ||           .|:.:|.|:.:||:         |::
Mouse   488 TVLCLVLTWWT---TPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLV 549

  Fly   464 --YLTIHKPVKWLADTSQAINLW 484
              ::.::..::..|.|.....:|
Mouse   550 SIFVNVYLMMQMTAGTWARFGIW 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	124/596 (21%)
Slc7a3	NP_031541.1	2A0303	4..588	CDD:273330	128/608 (21%)