Protein Alignment mnd and slc7a11

DIOPT Version :10

• Sequence 1: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_009289503.1
• Gene: slc7a11 / 100151597
• ZFINID: ZDB-GENE-150416-1
• Length: 498
• Species: Danio rerio
• Alignment Length: 487
• Identity: 210/487 - (43%)
• Similarity: 315/487 - (64%)
• Gaps: 18/487 - (3%)

  Fly    11 IPRQVFEVPPAEPNNSTADSG------------SQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFV 63
            :||:....|  .||.....|.            .....|:|:|::.||.|::||:|.|:|:|||:
Zfish     1 MPRRTVSAP--HPNGDPTPSNFGEKEPLKLNGEPPKEKVELRKKVTLLRGISIIIGTIIGAGIFI 63

  Fly    64 SPKGVLKFSGSIGQSLIVWVLSGVLSMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWV 128
            ||||:|:.|||:|.||:|||..|:||:.|||.||||||.|.||||.|.||..||||..||:.||.
Zfish    64 SPKGILQNSGSVGMSLVVWVACGILSLFGALSYAELGTCIKKSGGHYTYILEAFGPQVAFVRLWA 128

  Fly   129 ALLILVPTGNAITALTFAIYLLKPFWPSCDAPIEAVQLLAAAMICVLTLINCYNVKWVTRVTDIF 193
            .::.:.|.|.|:.||.|..|:|:|.:..|..|..|::|.....|.::..:|..:|.|..|:....
Zfish   129 DMIAIRPAGLAVIALAFGRYILEPIFMPCGVPEIAIKLATTIGITIVMYLNSMSVSWTARLQIFL 193

  Fly   194 TGTKVVALLVIVGAGVWWLFDGNTEHWDNPFSGGLQDPGYIALAFYSGLFSYSGWNYLNFVTEEL 258
            |.:|::|:.:|:..|::.||.|.|::::|.|.........:.||||||:::|:||.||||||||:
Zfish   194 TFSKLLAIAIIIVPGLYQLFKGETKNFENAFEVNTAQLTGLPLAFYSGMYAYAGWFYLNFVTEEV 258

  Fly   259 KDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGYMSWIMPFAVA 323
            ::|.|.:|.||||||.:|.:.|.:||:||::|:|.||:|:|:||||||.:|::|..|:.:|..||
Zfish   259 ENPERTVPLAICISMVIVMICYTLTNVAYYTVMSADELLASNAVAVTFAEKLMGNFSYAVPVFVA 323

  Fly   324 CSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDVYVLI 388
            .|.|||:||.:||.||:|||.:|.|.||..:|:|::...||:|::|.|..:|||:||:.|:|.|:
Zfish   324 LSCFGSMNGCLFAISRMFFVASREGQLPEVLSMIHIRRHTPLPAVIVLYPITLLILFLGDIYSLL 388

  Fly   389 NYVSYVEALFTLISVSGLLWMRYKQPKTERPIKVNLALPIIYLIVCLFLVIFSCTQTPYVVGIGT 453
            |::|::..||..::|.||:::|:.:|...||.||.:.:|.::...|.|:|..|....|...|||.
Zfish   389 NFMSFLRWLFIGVAVVGLIYLRFTRPDLPRPFKVPIFIPAVFSFTCFFMVFLSLYSDPINTGIGF 453

  Fly   454 IIILSGIPVYYLTIH---KPVKWLADTSQAIN 482
            .|.|:|||.||:.||   || ||....|.::|
Zfish   454 AISLTGIPAYYIFIHSKRKP-KWFQKFSDSMN 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mnd	NP_524074.1	2A0308	22..496	CDD:273332	207/476 (43%)
slc7a11	XP_009289503.1	2A0308	13..497	CDD:273332	205/473 (43%)