DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5114 and emb1345

DIOPT Version :9

Sequence 1:	NP_001246760.1	Gene:	CG5114 / 39624	FlyBaseID:	FBgn0036460	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_565615.1	Gene:	emb1345 / 817147	AraportID:	AT2G26060	Length:	352	Species:	Arabidopsis thaliana

Alignment Length:	392	Identity:	77/392 - (19%)
Similarity:	140/392 - (35%)	Gaps:	96/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DELQEIIELEE-QPLDEDDDDLEEVTLEQLEAR-------LAMAGGDDDEEEDEEELRDRERIAA 73
            |.:::.:||.| |.|:...|.:..|....:.:.       ||...||:.....|:....|....
plant     2 DLMEKNLELVEIQKLEGHTDRVWSVAWNPVSSHADGVSPILASCSGDNTVRIWEQSSLSRSWTC- 65

  Fly    74 ITDEATVTFKKHTAPVFACSLHPNYNWAVTGSEDDRAFVWET--STGDVLYEITEHKDTVTETHF 136
                .||..:.||..|.:|:..|:.....|.|.|....:|:.  |..:.:..:..|::.|....:
plant    66 ----KTVLEETHTRTVRSCAWSPSGQLLATASFDGTTGIWKNYGSEFECISTLEGHENEVKSVSW 126

  Fly   137 SHDGVYLATGDLAGDLFVFKVSE--KHDERPILTKIWEYSMSDMSWLFWHRAAHILLAGSDSGEV 199
            :..|..|||......:::::|.|  ::|...:||.    ...|:..:.||....:|.:.|....:
plant   127 NASGSCLATCSRDKSVWIWEVLEGNEYDCAAVLTG----HTQDVKMVQWHPTMDVLFSCSYDNTI 187

  Fly   200 FVF--RIPSGECKILP-------GQSSRCESGELSGDGKKLFTAYVNGSVKLW--DLKSCQVLID 253
            .|:  ....||.:.:.       |.||...|...:..|.|:.|...:.::|:|  |:...|
plant   188 KVWWSEDDDGEYQCVQTLGESNNGHSSTVWSISFNAAGDKMVTCSDDLTLKIWGTDIAKMQ---- 248

  Fly   254 VNESHPMGFGEITHAVVACERESPFYVCAEASGECSSGKGIRYNTSFHNKTIRK----------- 307
                             :.|..:|:......||             :|::||..
plant   249 -----------------SGEEYAPWIHLCTLSG-------------YHDRTIYSAHWSRDDIIAS 283

  Fly   308 -------MLFCTN-----NGPVSTI------QSEHGIECLAFAPSSADLKLFACGSLDGRISIWD 354
                   .||..:     :||...:      ..|:.:..:.::|...: :|.|..|.||.:.||.
plant   284 GAGDNAIRLFVDSKHDSVDGPSYNLLLKKNKAHENDVNSVQWSPGEGN-RLLASASDDGMVKIWQ 347

  Fly   355 YA 356
            .|
plant   348 LA 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5114	NP_001246760.1	WD40	79..439	CDD:295369	63/322 (20%)
		WD40	<81..441	CDD:225201	61/320 (19%)
		WD40 repeat	89..126	CDD:293791	8/38 (21%)
		WD40 repeat	132..170	CDD:293791	9/39 (23%)
		WD40 repeat	175..213	CDD:293791	8/39 (21%)
		WD40 repeat	220..299	CDD:293791	12/80 (15%)
		WD40 repeat	266..321	CDD:293791	11/83 (13%)
		WD40 repeat	326..365	CDD:293791	9/31 (29%)
		WD40 repeat	373..408	CDD:293791
		WD40 repeat	414..438	CDD:293791
emb1345	NP_565615.1	WD40	12..347	CDD:238121	72/378 (19%)
		WD40 repeat	23..71	CDD:293791	9/52 (17%)
		WD40 repeat	78..116	CDD:293791	7/37 (19%)
		WD40 repeat	121..160	CDD:293791	8/38 (21%)
		WD40 repeat	167..206	CDD:293791	7/38 (18%)
		WD40 repeat	216..263	CDD:293791	10/67 (15%)
		WD40 repeat	270..313	CDD:293791	5/42 (12%)
		WD40 repeat	320..346	CDD:293791	6/26 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910