DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5114 and SPR

DIOPT Version :9

Sequence 1:	NP_001246760.1	Gene:	CG5114 / 39624	FlyBaseID:	FBgn0036460	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_003115.1	Gene:	SPR / 6697	HGNCID:	11257	Length:	261	Species:	Homo sapiens

Alignment Length:	65	Identity:	15/65 - (23%)
Similarity:	28/65 - (43%)	Gaps:	21/65 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DELQEIIELEEQ----------PLDEDDDDLEEVTLEQLEARLAMAGGDDDEEEDEEELRDRERI 71
            |.|.:::.|||.          |||.|        ::||....::   |.|..:..:||:.:.::
Human   178 DMLFQVLALEEPNVRVLNYAPGPLDTD--------MQQLARETSV---DPDMRKGLQELKAKGKL 231

Fly 72 71
Human 232 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5114	NP_001246760.1	WD40	79..439	CDD:295369
		WD40	<81..441	CDD:225201
		WD40 repeat	89..126	CDD:293791
		WD40 repeat	132..170	CDD:293791
		WD40 repeat	175..213	CDD:293791
		WD40 repeat	220..299	CDD:293791
		WD40 repeat	266..321	CDD:293791
		WD40 repeat	326..365	CDD:293791
		WD40 repeat	373..408	CDD:293791
		WD40 repeat	414..438	CDD:293791
SPR	NP_003115.1	sepiapter_red	8..260	CDD:273660	15/65 (23%)
		adh_short	9..212	CDD:278532	11/41 (27%)
		Substrate binding. /evidence=ECO:0000250	157..158
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100610
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900