DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5114 and Poc1a

DIOPT Version :9

Sequence 1:	NP_001246760.1	Gene:	CG5114 / 39624	FlyBaseID:	FBgn0036460	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	XP_038937909.1	Gene:	Poc1a / 501048	RGDID:	1565004	Length:	405	Species:	Rattus norvegicus

Alignment Length:	364	Identity:	75/364 - (20%)
Similarity:	111/364 - (30%)	Gaps:	131/364 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 FKKHTAPVFACSLHPNYNWAVTGSEDDRAFVWETSTGDVLYEITEHKDTVTETHFSHDGVYLATG 146
            ||.|...|.......|.....:||.|....:|........|..|.|||.||..:||..|..||:|
  Rat    15 FKGHRDAVTCVDFSLNTKHLASGSMDSTLMIWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASG 79

  Fly   147 DLAGDLFVFKVSEKHDERPILTKIWEYSMSDMSWLFWHRAAHILLAGSDSGEVFVFRIPS--GEC 209
                            .|....:||                                :|:  ||.
  Rat    80 ----------------SRDKTVRIW--------------------------------VPNVKGES 96

  Fly   210 KILPGQSSRCESGELSGDGKKLFTAYVNGSVKLWDLKSCQVLIDVNESHPMGFGEITHAVVACER 274
            .:....::...|.....||:.|.||..:.:||:|.                     ||.
  Rat    97 TVFRAHTATVRSVHFCSDGQLLVTASDDKTVKVWS---------------------THR------ 134

  Fly   275 ESPFYVCAEASGECSSGKGIRYNTSFHNKTIRKMLFCTNNGPVSTIQSEHGIECLAFAPSSADLK 339
                                           ::.||       |..|..:.:.|..|:|   |.:
  Rat   135 -------------------------------QRFLF-------SLTQHINWVRCAKFSP---DGR 158

  Fly   340 LFACGSLDGRISIWD-YAKSALRTICENPVPNDAVIRIKWLNDHTILAATSQGN-LNAFDARTGI 402
            |....|.|..:.:|| .::..:.:.||:   ...|..:.:....|.:||....| :..:|.||
  Rat   159 LIVSASDDKTVKLWDKTSRECVHSYCEH---GGFVTYVDFHPSGTCIAAAGMDNTVKVWDTRT-- 218

  Fly   403 LKFTLTGHY-YH---IYEFVYKPQENLLLTVSEDNTAKI 437
              ..|..|| .|   :....:.|..|.|:|.|.|:|.||
  Rat   219 --HRLVQHYQLHSAAVNALSFHPSGNYLITASSDSTLKI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5114	NP_001246760.1	WD40	79..439	CDD:295369	75/364 (21%)
		WD40	<81..441	CDD:225201	75/364 (21%)
		WD40 repeat	89..126	CDD:293791	7/36 (19%)
		WD40 repeat	132..170	CDD:293791	8/37 (22%)
		WD40 repeat	175..213	CDD:293791	3/39 (8%)
		WD40 repeat	220..299	CDD:293791	11/78 (14%)
		WD40 repeat	266..321	CDD:293791	5/54 (9%)
		WD40 repeat	326..365	CDD:293791	9/39 (23%)
		WD40 repeat	373..408	CDD:293791	8/35 (23%)
		WD40 repeat	414..438	CDD:293791	9/24 (38%)
Poc1a	XP_038937909.1	WD40	11..299	CDD:238121	75/364 (21%)
		WD40 repeat	23..59	CDD:293791	6/35 (17%)
		WD40 repeat	64..100	CDD:293791	14/83 (17%)
		WD40 repeat	107..142	CDD:293791	14/99 (14%)
		WD40 repeat	148..184	CDD:293791	9/38 (24%)
		WD40 repeat	190..226	CDD:293791	10/39 (26%)
		WD40 repeat	232..255	CDD:293791	7/22 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53955
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010