DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5114 and mlst-8

DIOPT Version :9

Sequence 1:NP_001246760.1 Gene:CG5114 / 39624 FlyBaseID:FBgn0036460 Length:445 Species:Drosophila melanogaster
Sequence 2:NP_001249709.1 Gene:mlst-8 / 182509 WormBaseID:WBGene00015697 Length:382 Species:Caenorhabditis elegans


Alignment Length:381 Identity:77/381 - (20%)
Similarity:133/381 - (34%) Gaps:105/381 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 ITDEATVTFKKH----------TAPVFACSLHPNYNWAVTGSEDDRAFVWETSTGDV-------- 120
            :|.|.:...:||          ..|.|..|.|.   ..|:.|.|....:|:.|||..        
 Worm    20 MTPEKSFETEKHFQNTNQVPTEAPPSFDPSPHA---LLVSASYDLTIRLWQLSTGKCIGTIPHNE 81

  Fly   121 ------------------------LYEITEHKD---------TVTETHFSHDGVYLATGDLAGDL 152
                                    :|:::..||         .||...|...|.::.||   ||.
 Worm    82 GQVNALSLTSTGRDLAVGAWQKVRIYDVSSGKDPKATIELPKNVTVVGFEAAGRWMYTG---GDD 143

  Fly   153 FVFKVSEKHDERPILTKIWEYSMSDMSWLFWHRAAHILLAGSDSGEVFVF--------RIPSGEC 209
            .|.::.|..:.:.:..::..:..|.::.:..:.....|...::|..|:|:        |:|    
 Worm   144 GVCRIWEMRNNQLVANRLLSFPGSTVTSIVPNTHQTHLFVSTNSAHVWVWDVVNHIFMRLP---- 204

  Fly   210 KILPGQSSRCESGE---LSGDGKKLFTAYVNGSVKLWDLKSCQVLIDVNESHPMGFGEITHAVVA 271
              :|......|..:   :...||||......|.:..|||.:.:|:    ||  ..|......:|.
 Worm   205 --MPDDLKMQEFVQKLAVHPSGKKLTGITNKGRLLCWDLMTREVV----ES--SAFDMFKSPIVP 261

  Fly   272 CERESPFYVC---AEASGECSSGKGIRYNTSFHNKTI-----RKMLFCTNNGPV---STIQSEHG 325
            .|:::..|.|   .:...:...|.|:....|...|.|     .|.::..|:..:   .::|:|.|
 Worm   262 IEQDTGTYGCLRDEDKHYKMREGHGLSCRYSPDGKYIVASGSEKEVYVFNSETMEIKGSLQTECG 326

  Fly   326 IECLAFAPSSADLKLFACGSLDGRISIWDYAKS-----------ALRTICEN-PVP 369
            ....|.. ||....:|..|: |.::.|||...:           .|..:|.| |.|
 Worm   327 WNWDAIF-SSEGRYIFTGGN-DNQVKIWDVENNKKVAQWDGHIKPLTAMCMNGPTP 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5114NP_001246760.1 WD40 79..439 CDD:295369 75/376 (20%)
WD40 <81..441 CDD:225201 75/374 (20%)
WD40 repeat 89..126 CDD:293791 11/68 (16%)
WD40 repeat 132..170 CDD:293791 9/37 (24%)
WD40 repeat 175..213 CDD:293791 7/45 (16%)
WD40 repeat 220..299 CDD:293791 19/84 (23%)
WD40 repeat 266..321 CDD:293791 11/65 (17%)
WD40 repeat 326..365 CDD:293791 10/49 (20%)
WD40 repeat 373..408 CDD:293791
WD40 repeat 414..438 CDD:293791
mlst-8NP_001249709.1 WD40 46..353 CDD:392136 65/326 (20%)
WD40 repeat 46..79 CDD:293791 10/35 (29%)
WD40 repeat 85..121 CDD:293791 3/35 (9%)
WD40 repeat 125..165 CDD:293791 10/42 (24%)
WD40 repeat 170..204 CDD:293791 5/33 (15%)
WD40 repeat 215..274 CDD:293791 16/64 (25%)
WD40 repeat 286..325 CDD:293791 7/38 (18%)
WD40 repeat 332..352 CDD:293791 5/21 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53955
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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