DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5114 and taf5

DIOPT Version :9

Sequence 1:	NP_001246760.1	Gene:	CG5114 / 39624	FlyBaseID:	FBgn0036460	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_001135586.1	Gene:	taf5 / 100216139	XenbaseID:	XB-GENE-1004611	Length:	777	Species:	Xenopus tropicalis

Alignment Length:	398	Identity:	80/398 - (20%)
Similarity:	142/398 - (35%)	Gaps:	117/398 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NTPPHR----PDFDDGDDELQEIIELEE--QPLDEDDDDLEEV-------------TLEQLEARL 49
            |.||..    |:..| .|:|.:|:.::|  :.:....|.|..:             .::..:...
Frog   397 NAPPQNRIPLPELKD-SDKLDKIMIMKETAKRVRLGQDSLPSICFYTFLNAYQGLTAVDVTDDSS 460

  Fly    50 AMAGGDDD----------------EEEDEEELRDRER---IAAITDEATVTFKK----HTAPVFA 91
            .:|||..|                :...:..:.|:|.   :..|.||.:.:..|    |:.||:|
Frog   461 LIAGGFADSTVRVWSLTPKKLRSVKSASDLSIIDKESDDVLERIMDEKSSSEMKVLYGHSGPVYA 525

  Fly    92 CSLHPNYNWAVTGSEDDRAFVWETSTGDVLYEITEHKDTVTETHFSHDGVYLATGDLAGDLFVFK 156
            .|..|:.|:.::.|||....:|...|...|.....|...|.:|.||..|.|..:|   |...|.:
Frog   526 TSFSPDRNYLLSSSEDGTIRLWSLQTFTCLVAYKGHNYPVWDTQFSPYGYYFVSG---GHDRVAR 587

  Fly   157 VSEKHDERPILTKIWEYSMSDMSWLFWHRAAHILLAGSDSGEVFVFRIPSGEC-KILPGQSSRCE 220
            :......:|:  :|:...::|:....:|..::.:..||....|.::.:.:|.| :|..|......
Frog   588 LWATDHYQPL--RIFAGHLADVICTRFHPNSNYIATGSTDRTVRLWDVLNGNCVRIFTGHKGPIH 650

  Fly   221 SGELSGDGKKLFTAYVNGSVKLWDLKSCQVLIDVNESHPMGFGEITHAVVACERESPFYVCAEAS 285
            |...:.:||.|.|...:|.|.|||:           .|.:..||:
Frog   651 SLAFTPNGKFLATGASDGRVLLWDI-----------GHGLMVGEL-------------------- 684

  Fly   286 GECSSGKGIRYNTSFHNKTIRKMLFCTNNGPVSTIQSEHGIECLAFAPSSADLKLFACGSLDGRI 350
                  ||       |..|:..:.|                        |.|.::.:..|:|..:
Frog   685 ------KG-------HTNTVYALRF------------------------SRDGEILSSVSMDNTV 712

  Fly   351 SIWDYAKS 358
            .:||..|:
Frog   713 RLWDTVKA 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5114	NP_001246760.1	WD40	79..439	CDD:295369	60/285 (21%)
		WD40	<81..441	CDD:225201	60/283 (21%)
		WD40 repeat	89..126	CDD:293791	11/36 (31%)
		WD40 repeat	132..170	CDD:293791	9/37 (24%)
		WD40 repeat	175..213	CDD:293791	8/38 (21%)
		WD40 repeat	220..299	CDD:293791	15/78 (19%)
		WD40 repeat	266..321	CDD:293791	5/54 (9%)
		WD40 repeat	326..365	CDD:293791	7/33 (21%)
		WD40 repeat	373..408	CDD:293791
		WD40 repeat	414..438	CDD:293791
taf5	NP_001135586.1	TAF5_NTD2	188..320	CDD:176269
		WD40	<426..716	CDD:225201	68/362 (19%)
		WD40	449..719	CDD:238121	68/342 (20%)
		WD40 repeat	450..507	CDD:293791	7/56 (13%)
		WD40 repeat	524..560	CDD:293791	10/35 (29%)
		WD40 repeat	565..601	CDD:293791	11/40 (28%)
		WD40 repeat	608..643	CDD:293791	7/34 (21%)
		WD40 repeat	649..685	CDD:293791	13/72 (18%)
		WD40 repeat	691..737	CDD:293791	8/54 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910