Protein Alignment DCX-EMAP and eml1

DIOPT Version :10

• Sequence 1: NP_001261850.1
• Gene: DCX-EMAP / 39617
• FlyBaseID: FBgn0259099
• Length: 1118
• Species: Drosophila melanogaster
• Sequence 2: XP_021322902.2
• Gene: eml1 / 767643
• ZFINID: ZDB-GENE-060929-156
• Length: 840
• Species: Danio rerio
• Alignment Length: 766
• Identity: 272/766 - (35%)
• Similarity: 395/766 - (51%)
• Gaps: 106/766 - (13%)

  Fly   388 SRPSVVAAAPILPT----DELPKVPLRGARPRSKS-----------RPRILYAPESEILRPN--- 434
            :|| ::||.|:.||    ..|||   :|....|.|           |..:.....||.:.||
Zfish   102 ARP-MIAALPLRPTVNNGTVLPK---KGGTLPSPSNCKKDNNSPATRSTVKRTSSSEHVGPNNRK 162

  Fly   435 ---------------------GEYTMLDIMKEEPTKVTIRGLRRTFY--------------PPVH 464
                                 |:.| .:..:.||  |...|:||..:              |...
Zfish   163 DSGVDSKNNRTRAGSTGSNSSGKKT-TETKQREP--VFSAGMRRVTHCKDEGYVKMYLKGRPITM 224

  Fly   465 HAPAD-----------NSPPDKKLQLQWVHGYRGIDARRNLWVLPSGELLYYVAAVAVLFDRDED 518
            :.|.|           :.|| |||:|.||:||||.|.|.||::||:||.:|::|:|.||::.||.
Zfish   225 YMPKDLVDTYCLETKADLPP-KKLKLDWVYGYRGRDCRSNLYLLPTGETVYFIASVVVLYNVDEQ 288

  Fly   519 AQRHYTGHTEDIMCMDVHPSRELVASGQKAG--RDRKSQA-HVRIWSTESLQTLYVFGMGELDSG 580
            .||||||||:||.|:.|||.:..:|:||.||  .|.|..| |||:|.:.||.||::.|.|..|..
Zfish   289 LQRHYTGHTDDIKCLAVHPDKITIATGQVAGTSSDGKQLAPHVRVWDSVSLNTLHILGSGFFDRA 353

  Fly   581 VTAVAFSQLNGGSYILAVDSGRESILSVWQWQWGHLLGKVATLQEGLSGAAFHPLDDNLIITHGR 645
            :..::||:.||||::..||...:.:||||.||....|.:|....|.:..|.|||.|.|:|:|.|:
Zfish   354 LVCLSFSKSNGGSWLCVVDDSNDHMLSVWDWQREDRLAEVKCSNESVFAADFHPTDANIIVTCGK 418

  Fly   646 GHLAFWHR------RKDGFFERTDIVKQPSRSHVTSVQFEPDGDVITADSDGFITIYSVDSDGAY 704
            .||.||..      :|.|.||     ||.....|..|.|..:||.||.||.|.|.::   ..|:.
Zfish   419 SHLCFWSLEKGSLVKKQGLFE-----KQEKPKFVLCVTFSENGDAITGDSSGNILVW---GKGSN 475

  Fly   705 FVRTEFE-AHNKGIGCLIMLGEGTLLSGGEKDRKIAAWDSLQNYKKIADTKLPEAAGGVRTIYPQ 768
            .:....: ||...:..|.||..|||:||| ||||:.:||  :|::||...::||..|.|||:
Zfish   476 RISLAIQGAHEASVFALCMLRNGTLVSGG-KDRKLISWD--ENFQKIQTVEVPELYGPVRTV--- 534

  Fly   769 RPGRNDGNIYVGTTRNNILEGSLQRRFTQVVFGHGRQLWGLAAHPDDELYATAGHDKHVALW--R 831
            ..||.: .:.:|||:|.:|:|||...|..:..||..:||||..||....:.|.|||||:.||  .
Zfish   535 AEGRGE-TVLIGTTKNYVLQGSLDGEFIPITQGHTDELWGLTIHPLKHQFLTCGHDKHIYLWDSD 598

  Fly   832 KNKLIWTIQTGYECVALAFHPFG-TLAAGSTEGHLLVINCENGAVMLTLRVCGS-PLNCVAYNQV 894
            .::.|||........:..|||.| |:|.|...|..||::.|: ..::|:...|: .|:.:.::..
Zfish   599 SHQPIWTKTLEDSAQSAGFHPSGATVAVGMQTGRWLVLDTES-KDLVTVHTDGNEQLSVIRFSPD 662

  Fly   895 GDMIAMGSQNGSIYLFRVSRDGFSYKKVNKIRG-SQPLTHLDWSMDGNFVQTVTIDFDLLFWDAK 958
            |:.:|:||.:..||::.|:.:|..|.:|.|..| |..:||||||:|..::.:.:.|:::|:|...
Zfish   663 GNFLAIGSHDNYIYIYAVAENGKKYSRVGKCSGHSSFITHLDWSVDSQYLVSNSGDYEILYWIPS 727

  Fly   959 SLSPERSPIAMKDVKWLTNNCTVGFLVAGQWSNRYYSTTNTIVATCSRSAAHDMLASGDAEGYLR 1023
            ......|....:|::|.|..||:||.|.|.|.:.  |....|.|.|| |.|..:|.:||..|.:.
Zfish   728 VCKQVVSVETTRDIEWATFTCTLGFHVFGLWPDG--SDGTDINAVCS-SYAKRLLVTGDDFGKVH 789

  Fly  1024 LFRYPCISPRAEFHESKVYSGMLACVRFLCGDHTLITVGGTDASLMVWDIV 1074
            ||.:||...||..|....:|..:..|.||..|..|::.||.|.|:|.|.:|
Zfish   790 LFSFPCSQSRAPSHIYSGHSSHVTNVNFLFDDSHLVSTGGKDMSIMQWRVV 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCX-EMAP	NP_001261850.1	DCX	166..253	CDD:214711
		DCX2_RP_like	300..372	CDD:340590
		HELP	449..515	CDD:460922	32/90 (36%)
		WD40	520..562	CDD:459801	25/44 (57%)
		WD40 repeat	530..573	CDD:293791	21/45 (47%)
		WD40	548..959	CDD:441893	157/425 (37%)
		WD40 repeat	582..624	CDD:293791	16/41 (39%)
		WD40 repeat	627..664	CDD:293791	17/42 (40%)
		WD40 repeat	673..712	CDD:293791	12/39 (31%)
		WD40 repeat	718..801	CDD:293791	35/82 (43%)
		WD40 repeat	806..838	CDD:293791	15/33 (45%)
		WD40 repeat	846..880	CDD:293791	12/34 (35%)
		WD40	847..>1073	CDD:475233	78/228 (34%)
		WD40 repeat	886..918	CDD:293791	9/31 (29%)
		WD40 repeat	931..969	CDD:293791	11/37 (30%)
		WD40 repeat	1002..1037	CDD:293791	15/34 (44%)
eml1	XP_021322902.2	None